dyscohesive

dyscohesive

adjective A term of art referring to loosened intercellular connections, especially between epithelial cells, which is one of the histologic features of early malignancy.
References in periodicals archive ?
For instance, rhabdoid tumor of the kidney is composed of dyscohesive round or polygonal cells having a round or indented nucleus with a central eosinophilic nucleolus.
The tumor is composed of large, dyscohesive tumor cells with coarse chromatin, distinct nucleoli, and abundant amphophilic cytoplasm (Figure 2, b).
Lobular carcinoma in situ (LCIS) was defined as a lesion in which more than 50% of the acini of a terminal duct--lobular unit were dilated and completely filled by uniform, small, and dyscohesive cells with bland nuclei, uniform chromatin, and indistinct nucleoli, whereas ductal carcinoma in situ (DCIS) was characterized by a single cell population showing cytologic pleomorphism, presence of mitoses, or singlecell necrosis and an appropriate growth pattern in at least 2 duct spaces.