DNAH.bb.11

(redirected from dynein heavy chain 11, axonemal)

DNAH.bb.11

A gene on chromosome 7p21 that encodes a dynein heavy chain protein, which attaches to microtubules and hydrolyses ATP to ADP, mediating the movement of respiratory cilia and producing force towards the minus ends of microtubules.

Molecular pathology
DNAH11 mutations cause Kartagener syndrome (situs inversus totalis and immotile cilia syndrome 1) and male sterility.