PDE4C

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PDE4C

A gene on chromosome 19p13.11 that encodes a nucleotide phosphodiesterase, which plays a critical role in signal transduction by hydrolysing the second messenger cAMP to AMP or cGMP to GMP; it thereby plays a role in regulating physiological processes, including vascular proliferation and contraction, cardiac contractility, platelet aggregation, hormone secretion and immune cell activation.
References in periodicals archive ?
In the weird and wonderful world of Quahog, Peter's pet pooch Brian does all right by the ladies, so it's hard to imagine that loveable dunce Cleveland would appear to be more of a catch than our pontificating fourlegged friend.
A tip of the dunce cap goes to Brockton District Court Clerk Magistrate Kevin Creedon, who last week presided over a deal permitting R&B singer Bobby Brown to sidestep cocaine possession charges in return for mentoring the city's youth for a year.
If only they would wait their turn, he's deaf but not a dunce,
He was by no means the dunce of the class; another hapless flyer slammed into our bridge.
ZOE regained her crown as Strictly Come Dancing favourite last night - as dance-floor dunce Fiona Phillips was booted off.
Just like the mum who is convinced her little angel makes child prodigy Ruth Lawrence look a bit of a dunce, so cat owners believe their moggies are Einstein with paws.
In the other, sloppy teaching is enhanced by the non-consensual public exclamation of numerical dunce caps.
Highlights of today's weekend review include Paolo Di Canio's awesome goal against the dispirited Dons, the disgusting refusal of dunce ref Rob Harris to give Hammers three blatant penalties and Paul Scholes' classic strike against Bradford.
The disjunction between gallery refinement and naked dunce, exacerbated by several comical little lights and candles and by the slathered-on paint, produced a conflicted rhetoric of styles.
As of March 20, the man behind the word dunce is now officially a "blessed" of the church.
When a budding Mafia capo approached writer Ernest Volkman with an offer to tell his life's story, the young hoodlum probably never imagined that Volkman would conclude that he was an incompetent dunce who typified today's baby mobsters.
Miliband branded the Prime Minister "the Dunce of Downing Street" for selling of Royal Mail for PS3billion.