druggable

(redirected from drugability)

druggable

, drugable (drŭg′ă-bĕl)
1. Amenable to treatment with drugs or susceptible to alteration or manipulation with drugs.
2. In genetics, pert. to the ability of a molecule to regulate the function of an endogenous protein for the benefit of the organism.
druggabilitydrugability (-bil′ĭt-ē)
References in periodicals archive ?
Functional predictions for targets, such as interaction partners, biological functions and drugability, are crucial for drug discovery and disease modelling.
particularly in the demonstration of drugability of the validated targets to
Bio-assays early = an immediate focus on drugability = higher success; Less wet chemistry = more "shots on goal" per dollar invested; Without HTS or virtual library screening.
This collaboration aims to improve drugability features (increasing efficacy, potency, selectivity and stability, while reducing possibly unwanted side-effects such as toxicity) of one promising lead candidate peptide identified in animal venom by Atheris, Debiopharm and the Ecole polytechnique federale de Lausanne (EPFL).
IPA can support a wide range of research objectives across our target and biomarker discovery programs - such as providing insight into target efficacy, drugability and, increasingly, toxicity.
NeoGenesis, founded in 1997, has developed a highly efficient Chemical Genomics strategy that utilizes drug-like, small molecule ligands very early in the discovery process to empirically determine the biological utility and drugability of poorly characterized, disease-associated proteins.
In addition, we launched a new product offering, TargetStar(TM), that allows our pharmaceutical and biotech customers to predict the drugability of drug targets.
Thus, precise knowledge of the function of a particular cellular protein is gained, from which the protein's drugability properties can be determined.