drug-food interaction

drug-food interaction

the effect produced when some drugs and certain foods or beverages are taken at the same time. For example, grapefruit juice blocks the metabolism of some drugs in the GI tract, an action that can cause normal dosages of a drug to reach toxic levels in the plasma.
References in periodicals archive ?
Kim Valenza, RD, CDE, CDN, senior clinical dietitian at New-York-Presbyterian/Weill Cornell Medical Center, says that people can make three mistakes regarding drug-food interaction.
35) However, MAOIs have been well established as an effective intervention for people with treatment-resistant depression, and transdermal formulations may provide a valuable therapeutic option and eliminate the drug-food interaction.
For pharmacists and physicians, this guide provides current drug-drug and drug-food interaction information, as well as herbal products, based on current published biomedical data.
A series of five case reports of a suspected clinically significant drug-food interaction between warfarin (Coumadin) and cranberry juice has prompted the United Kingdom's Committee on Safety of Medicines and the Medicines and Healthcare Products Regulatory Agency to warn patients on the oral anticoagulant to limit consumption of cranberry juice or avoid it altogether, jacci Bainbridge, Pharm.
Drug Interaction Facts - drug-drug and drug-food interaction information, including detailed significance ratings, onset, severity ratings, documented effects, mechanisms, and management options
Ducharme performed several drug-drug and drug-food interaction trials with emphasis on gut wall inhibitory mechanistic pathways, a novelty at the time.
We perform in our own Phase I / IIa clinics first-in-man safety and tolerability studies pharmacokinetic, pharmacodynamic, drug-drug interaction, drug-food interaction and bioequivalence studies as well as studies in special patient populations (Phase IIa - "proof of concept") e.
Drug Interaction Facts, produced by Facts and Comparisons, contains drug-drug and drug-food interaction between thousands of brand and generic drugs.
Based on the recent quarterly update of Stockley's Drug Interactions, this pocket guide contains about 2,300 monographs that detail evidence-based information on common drug-drug, drug-herb, and drug-food interactions.
Drug-food interactions (DFIs) pose many challenges during drug treatment.
In 2010, the first novel oral anticoagulant (NOAC) that could be delivered in fixed doses, did not require routine laboratory monitoring, had a lower potential for drug -drug and drug-food interactions, and could be used in both inpatient (acute) and outpatient (chronic, long-term) settings was released.
The developed nations have clearly established the role of the community pharmacist in the counseling of patients, information, administration, dosage, side effects, and storage of drugs, and drug-drug and drug-food interactions.