drug-food interaction

drug-food interaction

the effect produced when some drugs and certain foods or beverages are taken at the same time. For example, grapefruit juice blocks the metabolism of some drugs in the GI tract, an action that can cause normal dosages of a drug to reach toxic levels in the plasma.
References in periodicals archive ?
For pharmacists and physicians, this guide provides current drug-drug and drug-food interaction information, as well as herbal products, based on current published biomedical data.
A series of five case reports of a suspected clinically significant drug-food interaction between warfarin (Coumadin) and cranberry juice has prompted the United Kingdom's Committee on Safety of Medicines and the Medicines and Healthcare Products Regulatory Agency to warn patients on the oral anticoagulant to limit consumption of cranberry juice or avoid it altogether, jacci Bainbridge, Pharm.
Drug Interaction Facts - drug-drug and drug-food interaction information, including detailed significance ratings, onset, severity ratings, documented effects, mechanisms, and management options
Ducharme performed several drug-drug and drug-food interaction trials with emphasis on gut wall inhibitory mechanistic pathways, a novelty at the time.
We perform in our own Phase I / IIa clinics first-in-man safety and tolerability studies pharmacokinetic, pharmacodynamic, drug-drug interaction, drug-food interaction and bioequivalence studies as well as studies in special patient populations (Phase IIa - "proof of concept") e.
Drug Interaction Facts, produced by Facts and Comparisons, contains drug-drug and drug-food interaction between thousands of brand and generic drugs.
0, including consumer-friendly drug-drug and drug-food interaction monographs.
29 /PRNewswire/ -- First DataBank, a wholly owned subsidiary of The Hearst Corporation, has announced plans to release consumer versions of their popular drug interaction modules -- Drug-Drug Interaction Module (DDIM(TM)) and Drug-Food Interaction Module (DFIM(TM)) -- on February 3, 2000.
In 2010, the first novel oral anticoagulant (NOAC) that could be delivered in fixed doses, did not require routine laboratory monitoring, had a lower potential for drug -drug and drug-food interactions, and could be used in both inpatient (acute) and outpatient (chronic, long-term) settings was released.
17] Pradaxa provides effective, predictable and reproducible anticoagulation with a low potential for drug-drug interactions and no known drug-food interactions, without the need for routine coagulation monitoring.
This quick-reference guide to common drug interactions for health care professionals like physicians, pharmacists, and nurses is based on the most recent quarterly update of Stockley's Drug Interactions and provides concise, evidence-based guidance on the management of common drug-drug, drug-herb, and drug-food interactions and how to manage them.
The REMS includes an updated Medication Guide and a communication plan to help reduce medication errors involving drug-food interactions and incorrect dosing intervals.