drug idiosyncrasy


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Related to drug idiosyncrasy: cumulative effect

drug idiosyncrasy

An unusual response to a drug. It can manifest as an accelerated, toxic, or inappropriate response to the usual therapeutic dose of a drug.
Synonym: idiosyncrasy of effect
See also: idiosyncrasy

drug idiosyncrasy

An abnormal individual response to a drug causing an effect quite different from that expected. Idiosyncracy is inherent in the person concerned and is usually due to a genetic anomaly. It may take the form of hypersensitivity so that the normal effect is produced by a dose which is a small fraction of the standard dose.
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