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drug holiday |
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drug holiday, a period of drug withdrawal to reverse ineffectiveness of a drug resulting from receptor desensitization or adverse effects that may result from chronic treatment. For example, after a 7- to 10-day drug holiday, levodopa responsiveness appears to be enhanced, and lower doses are required to produce a therapeutic effect. drug holiday Psychiatry A period in which a prescribed drug is proscribed, to evaluate baseline behavior or ↓ the dose of psychoactive drugs, and possibly incidence of tardive dyskinesia. See Tardive dyskinesia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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It took much longer for me to get the T-20 than I had expected, leaving me on a drug holiday for nearly 8 months, during which time my health declined. This has not seemed to occur in most controlled clinical trials, though the possibility of such resistance is very real and could occur if people attempt to take a drug holiday without the supervision of their doctor. Ideally, the decision to take a drug holiday will be made jointly by the family and the physician, with appropriate input from the camp staff and the child, well in advance of the camp session. |
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