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Drug Holiday

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drug holiday,
a period of drug withdrawal to reverse ineffectiveness of a drug resulting from receptor desensitization or adverse effects that may result from chronic treatment. For example, after a 7- to 10-day drug holiday, levodopa responsiveness appears to be enhanced, and lower doses are required to produce a therapeutic effect.

Drug Holiday
Therapeutics A time frame during which a drug is proscribed, to evaluate baseline behaviour or decreased the dose of psychoactive drugs, and possibly the incidence of tardive dyskinesia
Vox populi A trip to a place where some usually illicit drugs are legal—e.g., Amsterdam, Jamaica

drug holiday
Psychiatry A period in which a prescribed drug is proscribed, to evaluate baseline behavior or ↓ the dose of psychoactive drugs, and possibly incidence of tardive dyskinesia. See Tardive dyskinesia.


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In contrast, fewer than 5% of the 207 women in the cognitive cohort of the IBIS-II study of anastrozole versus placebo reported taking drug holidays over 24 months [5].
The efficacy of a drug holiday for patients receiving yearly zoledronic acid therapy and the appropriate timing of dentoalveolar surgery (if required) are unknown and therefore require further study.
The nausea is generally transient as long as patients don't take drug holidays.
 
 
 
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