drug eruption

eruption /erup·tion/ (ĕ-rup´shun)

1. the act of breaking out, appearing, or becoming visible, as eruption of the teeth.

2. visible efflorescent lesions of the skin due to disease, with redness, prominence, or both; a rash.erup´tive

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creeping eruption  cutaneous larva migrans.

drug eruption  an eruption or a solitary lesion caused by a drug taken internally.

fixed eruption  a circumscribed inflammatory skin lesion(s) recurring at the same site(s) over a period of months or years; each attack lasts only a few days but leaves residual pigmentation which is cumulative.

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drug eruption

n.

An eruption caused by ingestion, injection, inhalation, or insertion of a drug, often a result of allergic sensitization. Also called dermatitis medicamentosa, dermatosis medicamentosa, drug rash.

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drug eruption.

See drug rash.

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eruption [e-rup´shun]

1. the act of breaking out, appearing, or becoming visible, as eruption of the teeth.

2. visible efflorescent lesions of the skin due to disease, with redness, prominence, or both; a rash. adj., adj erup´tive.

creeping eruption

1. a peculiar eruption that appears to migrate, due to burrowing beneath the skin by certain larvae; it has the appearance of subcutaneous tunnels that are red and vesicular at the advancing end and dry and encrusted at older portions.

2. larva migrans.

drug eruption an adverse cutaneous reaction produced by ingestion, parenteral use, or local application of a drug, which may produce various morphologic patterns and types of lesions; called also dermatitis medicamentosa.

Kaposi's varicelliform eruption a generalized and serious vesiculopustular eruption of viral origin, superimposed on preexisting atopic dermatitis; it may be due to the herpes simplex virus (eczema herpeticum) or vaccinia (eczema vaccinatum).

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drug

1. any medicinal substance.

2. a narcotic.

3. to administer a drug.

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drug administration

includes aerosol, oral, transtracheal infusion, subcutaneous, intramuscular, intravenous, intrauterine, intraperitoneal, intra-articular, intramammary, intrathecal, subconjunctival, percutaneous, percutaneous intraruminal, gas inhalation. Mass medication is per feed or drinking water or, in the case of captive fish, in the tank water. For feral animals individual dosing by projectile dart is usual, for group therapy administration by bait is possible.

drug allergy

immune-mediated hypersensitivity to a drug molecule. Includes anaphylaxis, cutaneous reaction.

animal drug

a drug specifically tested for, and recommended for use in, animals. A legal point of importance if an animal dies as a result of an unusual or allergic reaction to medication with a drug not licensed for use in animals.

drug augmented swine dysentery

pigs receiving prophylactic medication are more severely affected than untreated pigs.

bactericidal/bacteriostatic drug

see antibiotic.

drug binding

binding of a drug to a large molecule in the tissues or fluids, e.g. binding to protein in the blood, may affect the metabolism of the drug, especially its rate of excretion.

chemotherapeutic drug

see chemotherapy.

drug combinations

a pharmaceutical strategy of combining several drugs into one formulation to provide for a specific requirement, e.g. an antibiotic combined with an anti-inflammatory agent in a mastitis ointment. Has the disadvantage that the dose of one drug is determined by the dose of the other.

controlled drug

availability and use of the drug is controlled by law. The control is at various levels of severity depending on the degree of danger associated with the uncontrolled use of each drug.

drug delayed swine dysentery

swine dysentery appears several days after treatment is discontinued.

drug delayed-augmented swine dysentery

after successful treatment during an attack of swine dysentery a more severe form of the disease occurs after treatment ceases.

drug diminished swine dysentery

the disease is reduced in severity as a result of treatment but is not eliminated.

drug eruption

an eruption or solitary skin lesion caused by a drug. See also dermatitis medicamentosa.

drug hypersensitivity

see drug allergy (above).

mutagenic d's

those that affect the DNA of the target organism have the hazard of creating new races of microorganisms with increased pathogenicity.

drug residue

the amount of the drug that can be detected in tissues at specified times after administration of the drug ceases. See also drug tolerance (below).

drug resistance

said mainly of antibacterial drugs and of microorganisms that are unaffected by the drug whilst most organisms of its species are susceptible. The resistance may be inherent or secondary to frequent exposure at sublethal levels. Resistance of an animal to a specific drug, e.g. to insulin, can also occur in this way.

drug resistant swine dysentery

medication of the feed is not an effective procedure and diarrhea and deaths occur.

drug safety margin

the magnitude of the difference between the dose required to produce a maximum therapeutic effect and that which produces a toxic effect. Registering authorities require this information.

drug selectivity

capacity to produce a single effect.

teratogenic drug

produces a toxic effect on the fetus at a particular phase of development producing a malformation.

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eruption

1. the act of breaking out, appearing or becoming visible, as eruption of the teeth.

2. visible efflorescent lesions of the skin due to disease, with redness, prominence, or both; a rash.

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creeping eruption

see cutaneous larva migrans.

drug eruption

see drug eruption.

tooth eruption

used in veterinary medicine as a guide to an animal's age.

grouped tooth eruption

permanent posterior teeth erupting side by side with no replacement horizontally.

sequential tooth eruption

permanent posterior teeth replaced by craniad movement of caudal teeth; seen in macropods and elephants.

tooth eruption times

see Table 19.