This data builds on the recently published studies in two high-impact peer-reviewed journals co-authored by international leading rheumatologists describing the 14-3-3eta protein as a "mechanistic" biomarker that is involved in driving disease
processes that lead to joint destruction.
The results from the Company's Phase 2a study suggest that immune system hyperactivation driving disease
progression can be specifically, rapidly and effectively reduced by AV-HALTs, resulting in a proportional restoration of immune system damage.
With more accurate accounts of individual gene variability driving disease
, therapy selection will be refined for patient success.
human activities are the most potent factors driving disease
Our next step is to understand if these play a role in driving disease
," he added.
This lack of consolidation makes it unclear how these different approaches relate in terms of understanding the mechanisms driving disease
This heterogeneity is why a single drug approach to treating cancer can be so ineffective - and why knowing the complete profile of the individual tumor cells driving disease
can help identify a personalized cocktail of drugs that target as many cancer cells as possible.
In clinical trials using monoclonal antibodies which neutralize IL-17 activity, its major role in driving disease
pathology has been concerned.
Ecological disturbances such as deforestation, intensive agricultural expansion, wildlife trade, and climate change - all human-induced changes to the environment - are driving disease
emergence and outbreaks with more frequency.
Degrading proteins that are driving disease
has the potential to bring about drastic changes in drug development, and we anticipate significant interest from pharmaceutical companies.
In order to advance closer to the reality of personalized medicine and highly predictive diagnostics, we need to better understand the signaling defects that are driving diseases
like cancer," said Chief Executive Officer Michael J.