drepanocytosis

drepanocytosis

occurrence of drepanocytes (sickle cells) in the blood.
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Each year, over 300,000 children are born affected by drepanocytosis and half of them die before the age of 5 years (Girot et al.
About 80% of children suffering from drepanocytosis do not receive medical care and die before the age of 5 years (Gini, 1985).
Drepanocytosis, also known as sickle cell anemia, is a genetic disease due to a mutation in position 6 within the [beta] chain of hemoglobin whereby glutamic acid, a polar amino acid, is replaced by valine, a non-polar amino acid.
Proposed therapies such as the medular implantation remain very expensive for most african population, who have recourse to medicinal plants in order to treat drepanocytosis (Begue and Castello-Herbreteau, 2001; Bernaudin, 1999; Neuwinger, 2000).
The present study was performed with the aim of listing the medicinal plants used to treat drepanocytosis and sold in various markets in Kinshasa, DRC.
Medicinal plants vendors mentioned 13 plants used to treat drepanocytosis in Kinshasa (Table 1).
Economic analysis of neonatal screening for drepanocytosis in metropolitan France.
Differential diagnosis eliminated other ulcerative diseases such as drepanocytosis, and the patient was HIV negative.