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John Langdon H., English physician, 1828-1896. See: Down syndrome.


1. Fine, soft, fluffy feathers forming the first plumage of a young bird and underlying the contour feathers in certain adult birds.
2. A soft, silky, or feathery substance, such as the first growth of a human beard.


Etymology: AS, adune, off hill
(of a computer) not operating as a result of malfunction or maintenance or for other reasons.


the soft, small feathers lacking BARBULES that cover the body of a bird and aid heat retention.

Patient discussion about down

Q. Can Down syndrome occur again? A few years ago, at the age of 32 my sister gave birth to a child that was diagnosed with Down syndrome. Now, at the age of 37 she's pregnant again. Can she have another baby with Down? Does the fact she has a baby with Down means she has higher risk for a second baby with Down?

A. - Older women especially after 35 years
- Previuosly child with Down Syndrome

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Q. assessment of down syndrom

A. down syndrome is a very easy diagnosis - it just need a chromosome check and seeing 3 (instead 2) chromosomes number 21. -

Q. what does enlarged heart mean? is it linked to down syndrome? My wife is 16 weeks pregnant. we did a prenatal US and we were told that the baby hes an enlarged heart and that we are advised to do amniocentesis. A friend of mine had a baby with down syndrome, and he was toled that if they have done this procedure, the doctors could have find it on time and abort the pregnancy. Is there a clear connection between the enlarged hart and the fact that the doctor advised us to do this procedure to down syndrome?

A. Down syndrome is associated with several kinds of heart problems. those problems can cause an enlarged heart but usually it will appears as a post-natal complication.
The protocol that most obstetrics use is that if there is anything abnormal in the US there is an automatic referral to an amniocentesis procedure.
the US has a lot of false alarms, so they must check with the more accurate procedure.

More discussions about down
References in classic literature ?
Grasping the corpse by an arm he tore the garment from it and then let the body float downward toward the temple.
As he lay resting on the skull-paved shelf, he saw in the center of the vault above the river another of those sinister round holes through which he momentarily expected to see a headless corpse shoot downward in its last plunge to a watery grave.
So, with a snort and a neigh and a whisk of his short tail he trotted off the roof into the air and at once began floating downward to the street.
But the moment before the water is reached, the head drops forward, the hands go out and lock the arms in an arch in advance of the head, and the body curves gracefully downward and enters the water just right.
Before a hand could stay him, the boy was over the rail and curving beautifully downward after the coin.
3% January drop and a flat ex-auto figure that followed downward revisions in both November and December.
Craig Carl Downward, 41, a roofer, was asleep in his van outside his home following a row with his girlfriend.
Downward displacement distances were measured, and the numbers of downward displacement or absent leaflets were compared with that of the surgery and with that of the two-dimensional-transthoracic echocardiogram (2D-TTE).
Lot 1 - CIG 6747336DCC - Zone Capital City and neighboring villages three years amount subject to downward 192 300 EUR excluding VAT, security charges not subject to downward 2 700 EUR excluding VAT.
25 mb/d, following a downward revision of 40 tb/d, mainly to reflect the high base-line effect.
4 percent increase from the previous month, revised downward from a preliminary reading of 2.
The MICEX index (daily) remains within the downward channel.