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John Langdon H., English physician, 1828-1896. See: Down syndrome.


1. Fine, soft, fluffy feathers forming the first plumage of a young bird and underlying the contour feathers in certain adult birds.
2. A soft, silky, or feathery substance, such as the first growth of a human beard.


Etymology: AS, adune, off hill
(of a computer) not operating as a result of malfunction or maintenance or for other reasons.


the soft, small feathers lacking BARBULES that cover the body of a bird and aid heat retention.

Patient discussion about down

Q. Can Down syndrome occur again? A few years ago, at the age of 32 my sister gave birth to a child that was diagnosed with Down syndrome. Now, at the age of 37 she's pregnant again. Can she have another baby with Down? Does the fact she has a baby with Down means she has higher risk for a second baby with Down?

A. - Older women especially after 35 years
- Previuosly child with Down Syndrome

Video link


Q. assessment of down syndrom

A. down syndrome is a very easy diagnosis - it just need a chromosome check and seeing 3 (instead 2) chromosomes number 21. -

Q. what does enlarged heart mean? is it linked to down syndrome? My wife is 16 weeks pregnant. we did a prenatal US and we were told that the baby hes an enlarged heart and that we are advised to do amniocentesis. A friend of mine had a baby with down syndrome, and he was toled that if they have done this procedure, the doctors could have find it on time and abort the pregnancy. Is there a clear connection between the enlarged hart and the fact that the doctor advised us to do this procedure to down syndrome?

A. Down syndrome is associated with several kinds of heart problems. those problems can cause an enlarged heart but usually it will appears as a post-natal complication.
The protocol that most obstetrics use is that if there is anything abnormal in the US there is an automatic referral to an amniocentesis procedure.
the US has a lot of false alarms, so they must check with the more accurate procedure.

More discussions about down
References in periodicals archive ?
Major Finding: Asking patients who have activity-limiting pain how much they've felt downhearted or depressed in the past 4 weeks identified depression with a sensitivity of 84% and a specificity of 43%.
It wasn't to be but we cannot be too downhearted because the players have given another terrific performance in both aspects.
TWO games and two defeats have left Atherstone Town's confidence at a low ebb but assistant manager Wayne Chapman is far from downhearted and looks for the tide to turn at Heath Hayes tomorrow.
Doctors told him it was too risky to play again, but he refused to be downhearted.
Now we just have to move on and not get downhearted about it.
IT is sad to see Christians being as downhearted as Dorothy Wedlake as we approach Christmas (Not All Santa's Little Helpers).
Wales, despite finishing with the wooden spoon in both the boys' and girls' events at the under-16 four-nations tournament in Cardiff, were not too downhearted.
However, Rees was far from downhearted after seeing his side beaten by six tries to one in the heart of the Massif Central.
Disappointing, yes, but this is not the time for the company to be downhearted, despite gloomy economic fears.
The Jockey Club's executive director Christopher Foster, who as IFHA joint vice-chairman ran the conference's regulatory session, was not downhearted.
Red-faced and downhearted, paleontologists are growing convinced that they have been snookered by a bit of fossil fakery from China.
Thomson was not too downhearted, saying: "It was a long way to come and not win a set, but I still enjoyed the experience.