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John Langdon H., English physician, 1828-1896. See: Down syndrome.


1. Fine, soft, fluffy feathers forming the first plumage of a young bird and underlying the contour feathers in certain adult birds.
2. A soft, silky, or feathery substance, such as the first growth of a human beard.


Etymology: AS, adune, off hill
(of a computer) not operating as a result of malfunction or maintenance or for other reasons.


the soft, small feathers lacking BARBULES that cover the body of a bird and aid heat retention.

Patient discussion about down

Q. Can Down syndrome occur again? A few years ago, at the age of 32 my sister gave birth to a child that was diagnosed with Down syndrome. Now, at the age of 37 she's pregnant again. Can she have another baby with Down? Does the fact she has a baby with Down means she has higher risk for a second baby with Down?

A. - Older women especially after 35 years
- Previuosly child with Down Syndrome

Video link


Q. assessment of down syndrom

A. down syndrome is a very easy diagnosis - it just need a chromosome check and seeing 3 (instead 2) chromosomes number 21. -

Q. what does enlarged heart mean? is it linked to down syndrome? My wife is 16 weeks pregnant. we did a prenatal US and we were told that the baby hes an enlarged heart and that we are advised to do amniocentesis. A friend of mine had a baby with down syndrome, and he was toled that if they have done this procedure, the doctors could have find it on time and abort the pregnancy. Is there a clear connection between the enlarged hart and the fact that the doctor advised us to do this procedure to down syndrome?

A. Down syndrome is associated with several kinds of heart problems. those problems can cause an enlarged heart but usually it will appears as a post-natal complication.
The protocol that most obstetrics use is that if there is anything abnormal in the US there is an automatic referral to an amniocentesis procedure.
the US has a lot of false alarms, so they must check with the more accurate procedure.

More discussions about down
References in periodicals archive ?
Ok, our defence was lacking tonight but it gives us a great deal to work on and we are far from downhearted.
Connections not in the least bit downhearted following defeat by subsequent Kempton winner Lord Sam.
Disappointing, yes, but this is not the time for the company to be downhearted, despite gloomy economic fears.
England captain Alec Stewart refused to be downhearted in the wake of a second one-day defeat in the NatWest triangular series after Australia won by five wickets at Bristol.
Red-faced and downhearted, paleontologists are growing convinced that they have been snookered by a bit of fossil fakery from China.
Nick's mood, since he mentions it, is low-key and plainly downhearted on this eclectic 10th solo effort.
As the nights get darker, And start to draw in, Let us not be downhearted, But let us begin, To admire the beauty that is all around, From the ablaze of colour that in Autumn is found.
However, last week my companions were downhearted and miserable.
TORQUAY boss Martin Ling refused to be downhearted following the draw with Oxford.
The result was enough to ensure it was Besiktas who won the group, but Pulis, who left all 11 players who had started against Tottenham last weekend at home and brought a squad of only 15, was not downhearted.
NORTHERN Ireland boss Nigel Worthington was not downhearted despite seeing his team given a testing Euro 2012 qualifying campaign.
The Turkish international says the Spaniards are not too downhearted as they expected a struggle even before going down to 10 men when Guille Franco was ordered off on 35 minutes.