Gene expression analysis of badh2 gene, gas chromatography-mass spectrometry assessment for quantitative analysis of 2AP combined with organoleptic analysis of phenotypic aroma represented that down-regulation
of the recessive badh2 allele is responsible for the significant elevation of 2AP concentration and phenotypic aroma expression in the studied aromatic rice genotypes.
05) of IRS-1, and significant down-regulation
of PEPCK (Pless than 0.
With more appetite neurons and fewer satiety neurons, as well as a down-regulation
of reward--and an abundance of available food--a newborn is at high risk of becoming obese.
Frequent deletions and down-regulation
of micro-RNAgenes miR15 and miR16at13q14 in chronic lymphocytic leukemia.
Fucoxanthin, derived from brown seaweeds, has shown anti-adipose capability through modulating the elevation of ROS, and down-regulation
of lipid metabolism genes.
sup], In addition, a recent investigation revealed that chronic miR221/222 mediated MGMT down-regulation
could render glioma cells unable to repair genetic damage.
The research also revealed that down-regulation
of Amdl was necessary for differentiation of ESCs into neural precursor cells and that Amdl is translationally regulated by a micro-RNA (miRNA), the first ever demonstration of miRNA-mediated regulation of the polyamine pathway.
The transgenic approach to produce high-oleic acid soybean oil is based on the down-regulation
of expression (gene silencing) of two soybean fatty acid desaturase genes termed FAD2-1A and FAD2-1B.
of 3[beta]-HSD may occur because B[a]P can negatively target 3[beta]-HSD, which is required for testosterone production.
These cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms (neoangiogenesis and down-regulation
of inflammation) toward tissue and bone repair and regeneration.
These changes were accompanied by activation of NF-kB thereby leading to enhanced levels of tumour necrosis factor-alpha, malondialdehyde and nitrite in liver and down-regulation
of hepatic antioxidant defense systems.
14) In addition, a higher frequency of down-regulation
of this complex has been observed for metastatic lesions than for primary lesions.