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down regulation

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down regulation
means of controlling hormone action where the number of hormone receptors at the cell surface is decreased by internalization of the receptor complex.
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Muscle fatigue with an aberrant spinal cord reflex preventing activation of golgi tendon organs in the muscle also leads to hyper-stimulation without down regulation.
Muscle cramping in endurance races by Elderbrock, Mark; Fieseler, Cathy / Running & FitNews
The HFE protein is involved in the down regulation of iron absorption that normally occurs with increasing iron status (9,11,15-22).
Phlebotomy Increases Cadmium Uptake in Hemochromatosis by Vahter, Marie / Environmental Health Perspectives
In short, pare down regulation and let the market sort out the winners and the losers.
Toward Competition in Local Telephony by Ford, George S. / Southern Economic Journal
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