double-blinded study

double-blinded study

A clinical trial in which neither the patient nor the researcher know which arm—e.g., gold standard therapy, experimental or placebo—of the study the patient has been placed, theoretically preventing patient or researcher bias.

A criticism of alternative medicine by mainstream medical practitioners is the former’s inability to reproduce claimed therapeutic results with double-blinded studies, which are the standards by which mainstream therapies are tested and approved by the FDA and other regulatory agencies.
References in periodicals archive ?
The ORIENT is a double-blinded study to examine the effectiveness of olmesartan medoxomil on patients with mild to moderate diabetic nephropathy.
Cyclacel has two additional compounds in development: seliciclib (CYC202) is being evaluated in a Phase IIb randomized double-blinded study as a third line treatment for patients with advanced non-small cell lung cancer (NSCLC) and sapacitabine (CYC682) is in Phase I clinical trials in solid and hematological cancers.
The primary endpoint of this placebo controlled, double-blinded study is the reduction in combined incidence of cardiovascular and cerebrovascular death, non-fatal myocardial infarction (heart attack) and non-fatal cerebral infarction (stroke), up to and including 30 days following CABG surgery.
In a double-blinded study, half drank Concord grape juice for eight weeks while the other half drank a calorie-matched placebo drink.
Gerard Francisco for several years and are confident we will see high-quality research come out of this randomized, double-blinded study.
The study is a double-blinded study, and Oxycyte recipients are not known at this point.
This is a double-blinded study, with both the patient and heart failure doctor unaware of which patients are receiving optimization therapy.
OTCBB:EVSC), Nutraceutical Development Corporation (NDC), a wholly-owned subsidiary of Endovasc Incorporated that develops nutraceutical products, announced today the results of a six-week double-blinded study to test the effectiveness of their nutraceutical product to enhance muscle mass and reduce body fat.
The prospective, randomized, double-blinded study followed the treatment of 891 adult women with clinical signs and symptoms of acute uncomplicated UTI, including pyuria, and a positive pre-therapy urine culture.
A total of 200 patients with AIDS-related Kaposi's sarcoma are being sought to participate in a multi-national Phase III randomized, placebo-controlled, double-blinded study of IM862 (developed by Cytran, Inc.
A total of 200 patients with AIDS-related Kaposi's sarcoma are needed to participate in a multi-national Phase III randomized, placebo-controlled, double-blinded study of IM862 (developed by Cytran, Inc.
This double-blinded study, to be conducted at the University of Los Angeles at California (UCLA), will assess the safety and pharmacological effects of paclitaxel in humans.