double-blind study


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Related to double-blind study: single blind experiment, single blind study

dou·ble-blind stud·y

a study in which neither the patients, the experimenter, nor any other assessor of the results, knows which participants are subject to which procedure, thus helping to ensure any biases or expectations will not influence results.
See also: double-blind experiment.

double-blind study

an experiment designed to test the effect of a treatment or substance by using groups of experimental and control subjects in which neither the subjects nor the investigators know which treatment or substance is being administered to which group. In a double-blind test of a new drug, the substance may be identified to the investigators by only a code. The purpose of a double-blind study is to eliminate the risk of prejudgment by the participants, which could distort the results. A double-blind study may be augmented by a cross-over experiment, in which experimental subjects unknowingly become control subjects, and vice versa, at some point in the study. See also placebo.

double-blind study

A study in which neither the subject nor the investigator nor the research team interacting with the subject or data during the trial knows what treatment a subject is receiving (e.g., active or placebo).

double-blind study

comparison of the effect of a drug or other intervention in a group of subjects with that of a placebo (an inactive 'fake' substance or procedure) in a second similar group, when neither those taking part as subjects nor the investigators observing the effects are aware of the group to which any subject has been allocated, until after completion of the study.

double-blind study

design of research study using active and placebo interventions, where neither the experimenter nor the subject is aware which is the true intervention

double-blind study,

n experimental technique in clinical research in which neither the researcher nor the patient knows whether the treatment administered is considered inactive (placebo) or active (medicinal).

dou·ble-blind stud·y

(dŭbĕl-blind stŭdē)
Study in which neither the patients, the experimenter, nor any other assessor of the results, knows which participants are subject to which procedure, thus helping to ensure that any biases or expectations will not influence results.

double-blind study

a study of the effects of a specific agent in which neither the administrator nor the recipient, at the time of administration, knows whether the active or an inert substance is given.
References in periodicals archive ?
When 30 adolescents with bipolar I disorder were randomized to receive either quetiapine (mean dose 432 mg/day) with divalproex or placebo with divalproex in a 6-week double-blind study, no differences in EPS ratings were noted between the two groups (J.
A post-hoc analysis of the results of a 545-patient, double-blind study of LUNESTA in patients with insomnia and co-existing Major Depressive Disorder (MDD) was conducted to determine whether reductions in patients' HAM-D17 scores (Hamilton Depression Rating Scale; a list of symptoms associated with depression) during the study were attributable to improvements in sleep with co-therapy relative to monotherapy.
In a controlled, double-blind study, researchers at Group Health Inc.
The double-blind study by an independent research group of 21 subjects taking BioAstin and 12 subjects taking a placebo found that subjects who took BioAstin for 56 days showed a significant increase of 93% in grip strength measurements (GSM) without pain.
Based on these and similar results in a double-blind study,Coffey concludes that "caffeine injections may be a potentially safe and highly effective technique to augment ECT.
The double-blind study by an independent research group of 15 subjects taking BioAstin and eight subjects taking Placebo found that subjects who took BioAstin for 56 days showed an average decrease in their measured CRP levels of over 20%.
His just-completed double-blind study involving 88 men not only indicates that cigarette smoke affects B-vitamin levels in the lung, but also suggests a link between this localized vitamin deficiency and lung cancer in smokers.
The double-blind study will test two doses of Androxal versus placebo and will include an open-label arm of the commercially available drug Androgel(R).
In an age-matched, double-blind study of patients diagnosed with osteoarthritis of the knee, researchers examined the impact of a topical administration of Celadrin(R) on participants.
based, double-blind study on MSM found the popular dietary supplement improved pain and function in people with knee osteoarthritis when compared to placebo.
The Phase II, multi-center, randomized, double-blind study is designed to evaluate the effect of a 4.