double helix


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helix

 [he´liks] (pl. he´lices, helixes) (Gr.)
1. a winding structure; see also coil and spiral.
2. the superior and posterior free margin of the pinna of the ear.
α-helix (alpha helix) the complex structural arrangement of parts of protein molecules in which a single polypeptide chain forms a right-handed helix.
double helix (Watson-Crick helix) the structure of deoxyribonucleic acid (DNA), consisting of two coiled chains, each of which contains information completely specifying the other chain.

Wat·son-Crick he·lix

(waht'sŏn crik),
the helical structure assumed by two strands of deoxyribonucleic acid, held together throughout their length by hydrogen bonds between bases on opposite strands, referred to as Watson-Crick base pairing. See: base pair.
[James Dewey Watson, Francis H. C. Crick]

double helix

n.
The coiled structure of double-stranded DNA in which strands linked by hydrogen bonds form a spiral configuration, with the two strands oriented in opposite directions.

double helix

A structural motif of nucleic acids in which 2 complementary chains of DNA and/or RNA spiral around each other as paired nucleobases attached to a deoxyribose phosphate backbone

Wat·son-Crick he·lix

(waht'sŏn-krik' hē'liks)
The helical structure assumed by two strands of deoxyribonucleic acid, held together throughout their length by hydrogen bonds between bases on opposite strands, referred to as Watson-Crick base pairing.
See also: base pair
Synonym(s): DNA helix, double helix.
[James Dewey Watson, Francis H. C. Crick]

double helix

see DNA.

Watson,

James Dewey, U.S. geneticist and Nobel laureate, 1928–.
Watson-Crick helix - the helical structure assumed by two strands of deoxyribonucleic acid. Synonym(s): DNA helix; double helix; twin helix

helix

1. a coiled structure.
2. the free margin of the pinna of the ear.

α-helix, alpha-helix
the folding arrangement of parts of protein molecules in which a single polypeptide chain forms a right-handed helix.
helix destabilizing proteins
proteins that bind in a cooperative manner to DNA single-strands during DNA replication and help open up the replication fork. Called also single-strand DNA binding proteins.
double helix
the native state of deoxyribonucleic acid (DNA), in which two antiparallel chains with complementary nucleotide sequences are wound around each other. The DNA molecule consists of two sugar-phosphate strands with the nucleotide base pairs stacked between them. The orientation of the two strands is antiparallel, i.e. 5′→3′ directions are opposite. Called also Watson-Crick helix.
References in periodicals archive ?
The structure is strange in that it features A-A binding (A normally pairs with T in DNA and or U in RNA) and, unlike the two anti-parallel strands of DNA, both halves of the poly(A) double helix run in the same direction.
With the purchase of Double Helix, McCann Health gets the basis for offering the best market research and access services in the business, the buyera[euro](tm)s chief executive John Cahill said.
In 25 years, the Double Helix Science Club has inspired hundreds of thousands of Australian kids who are passionate about science Maybe one day you'll find a job in science.
Watson has hinted more than once that he exaggerated personalities and situations in The Double Helix for intentional, novelistic effect.
A Konami presentation of a game developed by Double Helix for the PlayStation 3 and Xbox 360.
Stent, who wrote Molecular Biology of Bacterial Viruses, a textbook for the study of molecular genetics following the finding of the double helix, served as chair of the department of molecular biology at Berkeley from 1980 to 1986.
Like natural DNA, the new molecule can form a triple helix as well as a double helix.
Dampening System[TM]; STS Shock Terminator Suppressor[TM]; carbon cable guard rod w/Teflon slide; and Double Helix Elite[TM] string.
The following model is something that the student can easily grasp, can touch if needed, and seems to bring the concept of a double helix directly to them, including the nucleotide sequences.
The double helix was the physical shape of the strands of life they modeled using sheet metal and wire in a cold lab in Cambridge England.
explores the fundamental ideas that have led the public to consider the double helix of DNA to stand for genes and so the mechanism by which biological information is reproduced and inherited.
Crick's illustration of the double helix appeared in a seminal paper by her husband, Francis Crick, and James Watson in an April 1953 issue of the journal Nature.