dose-response curve

curve,

n a nonangular deviation from a straight line or surface.

curve, alignment,

n See alignment.

curve, anti-Monson,

n.pr See curve, reverse.

curve, compensating,

n the curvature of alignment of the occlusal surfaces of the teeth that is developed to compensate for the paths of the condyles as the mandible moves from centric to eccentric positions. A means of maintaining posterior tooth contacts on the molar teeth and providing balancing contacts on dentures when the mandible is protruded. Corresponds to the curve of Spee of natural teeth.

curve, dose-effect,

n a curve relating the dose of radiation with the effect produced.

curve, dose-response,

n a graphical representation of the relationship between dosage (x-axis) and degree of response (y-axis); used to determine the effective dose of any given drug.

curve, milled-in,

n See path, milled-in.

curve, Monson

n.pr the curve of occlusion, described by Monson, in which each cusp and incisal edge touch or conform to a segment of the surface of a sphere 8 inches (20 cm) in diameter, with its center in the region of the glabella. See also curve, compensating.

curve of occlusion (occlusal curvature),

n 1. a curved occlusal surface that makes simultaneous contact with the major portion of the incisal and occlusal prominences of the existing teeth.
2. the curve of a dentition on which the occlusal surfaces of the teeth lie. See also curve, reverse.

curve of Spee,

n.pr 1. an anatomic curvature of the occlusal alignment of teeth, beginning at the tip of the mandibular canine, following the buccal cusps of the natural premolars and molars, and continuing to the anterior border of the ramus, as described by von Spee.
2. the curve of the occlusal surfaces of the arches in vertical dimension, brought about by a dipping downward of the mandibular premolars, with a corresponding adjustment of the maxillary premolars.

curve of Wilson,

n.pr the curvature of the cusps, as seen from the front view. The curve in the mandibular arch is concave, whereas the one in the maxillary arch is convex.

curve, reverse,

n a curve of occlusion that is convex upward when viewed in the frontal plane.

curve, sine,

n the wave form of an alternating current, characterized by a rise from zero to maximum positive potential, then descending below zero to its maximum negative value, and then rising to its maximum positive potential, to fall to zero again.

curve, survival,

n a curve obtained by plotting the number or percentage of organisms surviving at a given time against a given dose of radiation. A curve showing the percentage of individuals surviving at different intervals after a particular dosage of radiation.

---

dose-response curve

A graphic representation of the effects that varous doses of an agent–eg, ionizing radiation or a chemotherapeutic agent, have on a given parameter–eg, cell viability, mutation frequency, DNA damage, tumor growth or metastasis or other behavior Therapeutics A graphic representation of the effectiveness or toxicity of a drug vs the dose administered