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dose-limiting side effects

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dose-limiting side effects,
drug effects that prevent a drug from being administered in higher doses.


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However, medication often has dose-limiting side effects that may cause a patient to decide to stop taking it after a short while.
Dose-limiting side effects can potentially restrict the use of optimally effective doses.
Although 5-FU is a mainstay of contemporary cancer therapy, it has some therapeutic drawbacks, including that it must be given intravenously, it can cause severe and dose-limiting side effects, and it has variable blood and tissue levels which impact its anti-tumor activity and safety profile.
 
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