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dose threshold

    0.01 sec.
dose threshold,
the minimum amount of a drug or absorbed radiation that produces a detectable effect.


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This translates to a dose threshold of >2 mg/d assuming a default market penetration of 1%.
An important 2004 study by the National Academy of Sciences concluded that "there is no compelling evidence to suggest a dose threshold below which the risk of tumor induction is zero.
Linear dose-response relationships were identified at sufficiently low doses, with no evidence of a dose threshold below which nanoparticle instillation ceased to cause inflammation.
 
 
 
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