dose threshold

dose threshold

the minimum amount of a drug or absorbed radiation that produces a detectable effect.
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Jude Children's Research Hospital investigators has found the chemotherapy dose threshold below which male childhood cancer survivors are likely to have normal sperm production.
One view holds that arsenic has a dose threshold below which exposures aren't harmful.
Deterministic effects are those radiobiological effects that increase in severity as the radiation dose increases and for which a dose threshold exists.
An important 2004 study by the National Academy of Sciences concluded that "there is no compelling evidence to suggest a dose threshold below which the risk of tumor induction is zero.
Exceeding the dose threshold of these random events only increases the probability of failure(s) occurring and not the certainty of failure.
The conclusions drawn by researchers were that visual function can be rescued and preserved in this animal model of disease utilizing ACT's GMP-manufactured human ES-derived RPE cells with a functional dose threshold and that these cells may provide an effective donor cell source to rescue photoreceptors in conditions like AMD, where RPE function is compromised.
In the future, radiological devices from Siemens will issue a warning message to the user if a certain dose threshold is exceeded in critical applications.
11), and [delta] is the threshold parameter such that the dose threshold for each individual chemical is given by [[delta].
The conclusions drawn by researchers were that visual function can be rescued and preserved in this animal model of disease utilizing GMP-compliant human ES-derived RPE cells with a functional dose threshold and that these cells may provide an effective donor cell source to rescue photoreceptors in conditions like Age-related macular degeneration (AMD), where RPE function is compromised.
Linear dose-response relationships were identified at sufficiently low doses, with no evidence of a dose threshold below which nanoparticle instillation ceased to cause inflammation.
Data modeling with the FSCR method provided maximum effect parameters (asymptotes) and dose threshold parameters for each chemical and for the mixture.
In vivo studies support a dose threshold for skin papilloma formation in response to TPA (2,3).