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dorzolamide/dor·zo·la·mide/ (dor-zo´lah-mīd) a carbonic acid anhydrase inhibitor, used as an antiglaucoma agent in the treatment of open-angle glaucoma and ocular hypertension; applied topically to the conjunctiva as the hydrochloride salt.
dorzolamideA CARBONIC ANHYDRASE inhibitor drug used in the form of eyedrops to treat open angle GLAUCOMA. A brand name is Trusopt.
carbonic anhydrase inhibitors
Drugs which inhibit the carbonic anhydrase enzyme in the ciliary epithelium of the ciliary body. This enzyme is essential for the formation of aqueous humour; its reduction results in a decrease in intraocular pressure. Those in use are sulfonamide derivatives. They are administered systemically (e.g. acetazolamide) or topically in the treatment of glaucoma. Examples: acetazolamide, brinzolamide, dichlorphenamide, dorzolamide.
a topical carbonic anhydrase inhibitor used in the treatment of glaucoma.