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dorsal horn |
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dorsal horn Etymology: L, dorsalis, back; AS, horn See posterior horn. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Joint nociceptors and dorsal horn neurons show increased responsiveness within hours after induction that continues to increase as the inflammation develops. These cells are in a lower brain area called the dorsal horn of the medulla, but are comparable to cells found in the spinal cord that respond to pain elsewhere on the body. The bombardment of neurons in the dorsal horn of the spinal cord by the primary afferent system stimulates N-methyl-D-aspartate (NMDA) receptors, increasing nociceptive signal transmission to the CNS, and may overwhelm pain control centers. |
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