dorsal horn


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dorsal horn

Etymology: L, dorsalis, back; AS, horn

dorsal horn

The main column of neuron cell bodies and unmyelinated cell processes (ie, gray matter) running through the dorsal quadrant of each half of the spinal cord. In stained cross-sections of spinal cord, the gray matter forms the rough shape of a butterfly; the dorsal horns are the upper wings.
Synonym: posterior horn See: spinal cord
See also: horn
References in periodicals archive ?
24, 26) We have shown that BDNF may cause downregulation of the chloride transporter KCC2 in a subpopulation of lamina I secondary sensory neurons in dorsal horn, which then causes a depolarizing shift in the anion reversal potential ([E.
Western blotting results showed that FGFR3 and GFAP expression was significantly increased in the spinal dorsal horn of SNI rats.
sup][8] Specifically, ERK activation in spinal cord dorsal horn neurons occurs by nociceptive activity by regulating the activity of glutamate receptors and potassium channels, as well as inducing gene transcription.
Formalin, when injected in the hind paw, is known to increase c-Fos expression in the spinal dorsal horn ipsilateral to the injection site.
Finally, inhibition is caused by the use of drugs that prevent the release of neurotransmitters in the dorsal horn required for pain transmission.
Downregulation of M4 but not M2 muscarinic receptors in the dorsal horn after peripheral nerve injury relates to responsiveness to SCS.
Prolonged primary afferent induced alterations in dorsal horn neurones, an intracellular analysis in vivo and in vitro.
In chronic pain models, there is a decrease in the number of opioid receptors in the dorsal horn of the spinal cord at the level of the injury but an increase in the number of [CB.
After removing the receptor protein from the dorsal horn, the itch was stopped and there was no impact on any other sensory sensations, such as pain, touch and temperature, meaning they had found the biocircut that causes itchy feelings.
The cells were distributed mainly in the dorsal horn.
It features increased excitation at the level of the dorsal horn nuclei and inhibition of descending pathways responsible for diffuse noxious inhibitory control.