For instance, the dopaminergic receptor
genes DRDla and DRD2 were differentially expressed 2 days after reperfusion after stroke in mice (Sieber et al.
4) Later, further gene variants of dopamine receptors, transporter or other regulator genes were discovered related to low dopaminergic receptor
function (5) and low dopamine release.
Hence, the presence of the A1 allele of the D2 dopaminergic receptor
gene polymorphism has been indicated as a possible factor for the emergence of certain movement disorders such as dystonia.
Influence of nitric oxide on morphine-induced amnesia and interactions with dopaminergic receptor
Neurogenetics of dopaminergic receptor
supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART).
An emerging theory starts linking OTR and VRS to the dopaminergic receptor
region as a 'reward center' (109).
1] activity antagonists that reverted the effects of d-amphetamine on the quarter life, it could be thought that this subtype of dopaminergic receptor
could have a greater implication in the perception of time.
Ejaculatory disturbances, diminished sexual desire, and erectile dysfunction associated with risperidone have been reported and several mechanisms including central dopaminergic receptor
blockade, a-adrenergic antagonism, and prolactin elevation have been proposed (17,18,19,20).
If confirmed it will suggest that NAAT "normalizes" brain abnormalities associated with drug dependence (alcohol, heroin and psychostimulants) induced by dopaminergic deficiency by acting as a dopaminergic receptor
agonist during protracted abstinence in polydrug abusers.
8] Domperidone, a peripheral D2 dopaminergic receptor
antagonist, is administered prior to apomorphine for prevention of nausea, vomiting, drowsiness and orthostasis.
Moreover, pimavanserin has no appreciable affinity for dopaminergic receptors
, and therefore does not induce motor adverse effects.
It also has a high affinity for dopaminergic receptors
, mainly D2, D3, and D4; muscarinic M1-5; (alpha-1) [alpha]-1 adrenergic; and histaminergic H1 receptorsin vitro.