dopamine receptors


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dopamine receptors

Nerve cell membrane binding sites that are activated by dopamine molecules. Some are excitatory and some inhibitory, but both classes contain many subtypes. Some of these receptors mediate behavioural effects.
References in periodicals archive ?
There is good evidence that prolactin-secreting cells in the pituitary gland are under inhibitory control of dopamine, and that these cells can show striking proliferation under conditions of physiologic demand [such as during pregnancy] or when dopamine receptors are blocked.
So, the researchers theorized that some drug users become addicts as a way of making up for a shortage of dopamine receptors.
Exercise has been found to increase dopamine release and to raise the number of dopamine receptors," he says.
The substance P (SP) heptapeptide fragment SP1-7 alters the density of dopamine receptors in rat brain mesocorticolimbic structures during morphine withdrawal.
Previous brain scans have suggested that the obese have fewer dopamine receptors in their brains than lean people.
He said it's the same type of mechanism that's at work in drug and alcohol addiction, which hijacks the same dopamine pathways and pushes a person to use more and more of the substance as dopamine receptors shut down.
Tardive dyskinesia (TD) is a chronic movement disorder caused by prolonged exposure to medications that block dopamine receptors, including antipsychotic drugs and some drugs used to treat nausea.
That structure's two types of dopamine-responsive cells are differentiated by the types of dopamine receptors, referred to as D1 and D2, on their surfaces.
But when the affected mice were treated with a drug that was able to activate dopamine receptors, the problem was reversed and the mice became more active and lost weight.
Imaging of dopamine receptors in the nigrostriatal pathway under the influence of a typical antipsychotic drug reveals an almost total blockade (approaching 90% of receptor sites).
Thioridazine is known to inhibit dopamine receptors.
The same proteins, called dopamine receptors, are present on some breast cancer stem cells.