dopamine receptor


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to dopamine receptor: dopamine receptor D2

dopamine receptor

Any of at least six receptors that bind dopamine in the brain. They influence body movements and emotional states. The dopamine receptors are designated D1, D2a, D2b, D3, D4, and D5. Each has an identifiably different function. The D2a receptor, for example, has a strong affinity for antipsychotic drugs, such as haloperidol.
See also: receptor
References in periodicals archive ?
He suspects that a particular form of the D2 dopamine receptor gene serves as a "gateway gene" that predisposes people to giving all sorts of drugs an initial try.
Samples from individuals diagnosed with alcoholism showed significantly fewer brain-cell binding sites for the dopamine receptor controlled by the chromosome 11 gene, as well as impaired binding function at those sites, the team reports in the July ARCHIVES OF GENERAL PSYCHIATRY.
The investigators calculated the proportional reporting ratio, "a ratio similar in concept to the relative risk ratio," between these cases and each individual dopamine receptor agonist.
MDS is thought to be the result of a compensatory up regulation of dopamine receptors due to the potent receptor blockade of the typical antipsychotics (as demonstrated by the PET scans discussed above).
In this paper we have tested pole-climbing time in Parkinson's disease mice, determined the levels of DA and HVA in striatum, analyzed the levels of dopamine receptor 1 and dopamine receptor 2 in striatum and the level of Caspase-3 protein in substantia nigra, by which we can investigate the mechanism of extract of Acanthopanax senticosus Harms against Parkinson's disease.
Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers.
The Vanderbilt experiments, published in Psychopharmacology (January 2008), are the first to demonstrate a link between behavior and the activity of dopamine receptors in response to an aggressive event.
Differential effects of dopamine receptor subtype blockade on performance of rats in a reaction-time paradigm.
The monkeys in the enriched environment had 20 percent more dopamine receptor function.
Apomorphin is a dopamine receptor antagonist which is indicated for the treatment of advanced Parkinson's disease.
TAIWAN--As reported in Annals of Pharmacotherapy (September 2002), symptoms of psychosis developed in two patients after treatment with the dopamine receptor antagonist metoclopramide.
The theory behind the study is that certain foods stimulate a transmitter in the brain called the dopamine receptor, which produces feelings of pleasure.