domoic acid


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domoic acid

(də-mō′ĭk)
n.
A water-soluble amino acid found in various marine algae that is a potent, often deadly neurotoxin to humans when consumed in contaminated mussels, clams, crabs, and anchovies.

domoic acid

An excitatory kainic acid analogue and neurotoxic glutamate agonist, which ↑ neuronal activity, causing food poisoning

domoic acid

C15H20NO6, a toxin that resembles glutamate, the main excitatory amino acid of the brain. When ingested, it may cause continuous seizures.
CAS # 14277-97-5
See also: acid
References in periodicals archive ?
Domoic acid gets broken down easily in water and by sunlight, but once the clumped algae are buried in the sediment, the toxin may stay protected until a bottom-dwelling organism eats it.
Domoic acid is a tricarboxylic acid produced by certain species of the cosmopolitan diatom Pseudo-nitzschia (Wright et al.
HPLC Detection of Domoic Acid in Phytoplankton Using Fluorenylmethoxycarbonyl (FMOC) Derivatization
A domoic acid outbreak in 1961 was believed responsible for the strange behavior of hundreds of birds in Capitola, which inspired Alfred Hitchcock to make his film "The Birds.
When levels of domoic acid fall below the action level, razor clam harvest may again be allowed.
Domoic acid production in Nitzschia isolated from a shrimp-culture pond in Do Son, Vietnam.
Officials took a sample from the dead whale to be tested for domoic acid poisoning, but even if a whale has been exposed to the acid, the toxin probably wouldn't kill it, authorities said.
Compared to controls, rats exposed to domoic acid had greater memory loss following administration of scopolamine, with the highest-dose group performing the worst.
It's something I never thought I would see in my lifetime,'' Fischer said of the recent problems with domoic acid and stranded sea lion pups in Ventura County.
Regulatory Limit for Domoic Acid (20 [micro]g DA/ g Tissue)
Domoic acid contamination of mussels in Canada in 1987 led to a food poisoning outbreak involving 107 patients, some of whom experienced severe gastrointestinal and neurologic symptoms and pathology of the hippocampus, the main target region of the brain.
More than 100 sea lions have filled rehabilitation centers in Santa Barbara and San Pedro, in part because of poisoning by domoic acid, a nerve toxin produced in the ocean at this time of year by algae.