dobutamine


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dobutamine

 [do-bu´tah-mēn]
a synthetic catecholamine administered parenterally as the hydrochloride salt for inotropic support in short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

dobutamine

/do·bu·ta·mine/ (do-bu´tah-mēn) a synthetic catecholamine having direct inotropic effects; used as the hydrochloride salt in the treatment of congestive heart failure and low cardiac output.

dobutamine

Cardiology A β—agonist used to treat standard therapy-refractory acute CHF; in contrast to other beta agonists, e.g., isoproterenol, dobutamine is not associated with a ↑↑↑ in myocardial O2 consumption–MOC, which precluded their use; dobutamine has only moderate vasodilating activity, ↑ cardiac output with little change in MOC. See Vascular-Ventricular coupling.

dobutamine

A drug used to assist in the management of HEART FAILURE. It increases the force of the contraction (inotropic agent) of the muscle of the ventricles and improves the heart output. It may be given by continuous intravenous drip. Brand names are Dobutrex and Posiject.

dobutamine

a synthetic catecholamine used as the hydrochloride and administered parenterally for inotropic support in short-term treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
References in periodicals archive ?
The requirement for catecholamines such as dobutamine are an independent risk factor for death in patients with heart failure and undergoing cardiac surgery (44,45).
Ruffolo played a significant role in the discovery and/or development of a number of marketed products, including carvedilol (Coreg/Kredex) for the treatment of congestive heart failure and hypertension, dobutamine (Dobutrex) for the acute management of congestive heart failure, ropinirole (Requip) for Parkinson's Disease, eprosartan (Teveten) for hypertension.
Patients treated with the vasodilator nitroglycerin or the natriuretic peptide nesiritide had better survival rates and shorter hospital stays than did those treated with the positive inotropic agents dobutamine and milrinone, the researchers said.
Gradients may be provoked with maneuvers, which increase contractility and/or decrease preload (such as dobutamine, the Valsalva maneuver, or exercise).
Negative interference by the catecholamines dopamine and dobutamine has recently been reported in methods that use hydrogen peroxide and horseradish peroxidase to generate chromophores [1-3].
Yalcin F, Muderrisoglu H, Korkmaz ME, Ozin B, Baltali M, Yigit F The effect of dobutamine stress on left ventricular outflow tract gradients in hypertensive patients with basal septal hypertrophy.
A central line was inserted and dobutamine (15 [micro]g/kg/minute), noradrenaline (0.
Projections are also provided for the number of studies involving pharmacologic stressing with intravenous adenosine, intravenous dipyridamole, intravenous regadenoson and intravenous dobutamine.
Dobutamine stress echo or SPECT scanning with pharmacologic vasodilator stress is recommended for women incapable of exercise.
He was transferred to the coronary care unit for more intensive intravenous inotropic therapy, including dobutamine 2.
Contrast and Harmonic Imaging Improves Accuracy and Efficiency of Novice Readers for Dobutamine Stress Echocardiography.