dobutamine


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dobutamine

 [do-bu´tah-mēn]
a synthetic catecholamine administered parenterally as the hydrochloride salt for inotropic support in short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

dobutamine

/do·bu·ta·mine/ (do-bu´tah-mēn) a synthetic catecholamine having direct inotropic effects; used as the hydrochloride salt in the treatment of congestive heart failure and low cardiac output.

dobutamine

Cardiology A β—agonist used to treat standard therapy-refractory acute CHF; in contrast to other beta agonists, e.g., isoproterenol, dobutamine is not associated with a ↑↑↑ in myocardial O2 consumption–MOC, which precluded their use; dobutamine has only moderate vasodilating activity, ↑ cardiac output with little change in MOC. See Vascular-Ventricular coupling.

dobutamine

A drug used to assist in the management of HEART FAILURE. It increases the force of the contraction (inotropic agent) of the muscle of the ventricles and improves the heart output. It may be given by continuous intravenous drip. Brand names are Dobutrex and Posiject.

dobutamine

a synthetic catecholamine used as the hydrochloride and administered parenterally for inotropic support in short-term treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
References in periodicals archive ?
Ruffolo played a leading role in the discovery and/or development of a number of now-marketed products, including carvedilol, dobutamine, ropinerole and eprosartan.
There was statistically significant correlation between preoperative HbA1C and preoperative stroke, preoperative MI history, Left atrial (LA) size, preoperative levosimendan, preoperative clopidogrel, postoperative AF, postoperative dopamine and dobutamine use, IABP, duration of extubation time, 24-hour chest tube drainage, duration of ICU and hospital mortality.
Dobutamine is a synthetic catecholamine which directly stimulates both beta-1 and beta-2 receptors.
We document the release of BNPsp, N-terminal pro-B-type natriuretic peptide (NT-proBNP), and troponin T as measured with a high-sensitivity assay (hsTnT) during dobutamine stress echocardiography (DSE) in patients with coronary artery disease (CAD) and in healthy volunteers.
1) In the particular case of right ventricular (RV) failure, dobutamine has been shown to improve RV contractility and cardiac output.
One interesting additional aspect of STICH was the viability study carried out in a subset of 601 patients using either dobutamine echocardiograms or SPECT stress testing.
9,10) Vasodilators, such as adenosine and dipyridamole, can exacerbate bronchospasm; therefore, they are contraindicated in patients with severe asthma and are replaced with dobutamine.
3], whereas dopamine, dobutamine, glucocorticoids, phenytoin, bromocriptine, and octreotide may suppress thyroid-stimulating hormone.
The course aims to educate the clinician on the basics on the 3 different types of stress tests including graded exercise tests, dobutamine tests, and adenosine tests.
The active agent in Liprostin(TM) (PGE-1) also improves liver and kidney function by stabilizing the cell membranes and protecting against free radical related damage to cells, and is as effective as dobutamine as a bridge to transplant.