Also found in: Wikipedia.
a synthetic catecholamine administered parenterally as the hydrochloride salt for inotropic support in short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
dobutamine/do·bu·ta·mine/ (do-bu´tah-mēn) a synthetic catecholamine having direct inotropic effects; used as the hydrochloride salt in the treatment of congestive heart failure and low cardiac output.
dobutamineCardiology A β—agonist used to treat standard therapy-refractory acute CHF; in contrast to other beta agonists, e.g., isoproterenol, dobutamine is not associated with a ↑↑↑ in myocardial O2 consumption–MOC, which precluded their use; dobutamine has only moderate vasodilating activity, ↑ cardiac output with little change in MOC. See Vascular-Ventricular coupling.
dobutamineA drug used to assist in the management of HEART FAILURE. It increases the force of the contraction (inotropic agent) of the muscle of the ventricles and improves the heart output. It may be given by continuous intravenous drip. Brand names are Dobutrex and Posiject.
a synthetic catecholamine used as the hydrochloride and administered parenterally for inotropic support in short-term treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.