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dobutamine |
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dobutamine /do·bu·ta·mine/ (do-bu´tah-mēn) a synthetic catecholamine having direct inotropic effects; used as the hydrochloride salt in the treatment of congestive heart failure and low cardiac output. dobutamine a synthetic catecholamine used as the hydrochloride and administered parenterally for inotropic support in short-term treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures. dobutamine Cardiology A β—agonist used to treat standard therapy-refractory acute CHF; in contrast to other beta agonists, e.g., isoproterenol, dobutamine is not associated with a ↑↑↑ in myocardial O2
consumption–MOC, which precluded their use; dobutamine has only moderate vasodilating activity, ↑ cardiac output with little change in MOC. See Vascular-Ventricular coupling. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Using intramucosal pH measured by gastric mucosal tonometry as a marker for tissue oxygenation, Silverman and Tuma (24) compared the effectiveness of dobutamine administration with the effectiveness of transfusion in increasing this parameter. Intravenous therapies included fluids, vasopressors, and inotropic agents, including dobutamine, dopamine, and norepinephrine. Medical therapy was optimized prior to IMT and included the use of digoxin, diuretics, and angiotensinconverting enzyme inhibitor agents by all subjects; intravenous dobutamine was administered to eight subjects. |
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