divalproex


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divalproex

 [di-val´pro-eks]
an anticonvulsant, used as divalproex sodium, a 1:1 compound of valproate sodium and valproic acid in treatment of migraine, manic episodes of bipolar disorder, and epileptic seizures, particularly absence seizures.

divalproex

/di·val·pro·ex/ (di-val´pro-eks) an anticonvulsant, used as d. sodium, a 1:1 compound of valproate sodium and valproic acid, in the treatment of migraine, manic episodes of bipolar disorder, and epileptic seizures, particularly absence seizures.

divalproex

(dī-văl′prō-ĕks′)
n.
A combination of the drugs valproate and valproic acid, used primarily to treat mania in bipolar disorder and seizures.

carbamazepine

An anticonvulsant used to manage partial seizures and generalised tonic-clonic seizures in children, bipolar disorder and trigeminal neuralgia; in contrast to valproate, carbamazepine is associated with better seizure control, fewer seizures and longer time to first seizure. 

Adverse effects
Dizziness, drowsiness, unsteadiness, nausea, vomiting, myelosuppression (up to 8-fold increase) in aplastic anaemia and agranulocytosis, rash, hair loss.

divalproex

a salt of valproic acid.
References in periodicals archive ?
Lab monitoring requirements for drugs, such as clozapine, lithium, or divalproex, could affect a patient's willingness to adhere.
For patients with mixed symptoms during mania, atypical antipsychotics and divalproex are effective.
The amount of alprazolam was halved to 1mg/day while the dose of divalproex sodium remained at 1000mg/day.
Patients on lithium plus placebo had a 40% greater risk of recurrence of a mania event than those on divalproex plus placebo.
Divalproex sodium has shown effectiveness in treating bipolar disorders in children and adolescents (Wagner et al.
After stopping any current medications, the youngsters took divalproex for 12 weeks and underwent periodic reevaluations.
Divalproex with as-needed benzodiazepines reduces the duration of withdrawal and risk of medical complications.
15, 2016; and Divalproex Sodium (Epival) 250 mg enteric coated tablet, with registration number DRXY34509, lot number 44762XP and expiry date of Aug.
For episodic migraine, all approved drugs--such as topiramate, opiramate, divalproex, timolol, and propranolol--are effective in reducing monthly migraine frequency, but similarly increase risk of adverse effects and treatment discontinuation.
M2 EQUITYBITES-August 23, 2013-Dr Reddya[euro](tm)s Laboratories unveils US FDA approved Divalproex Sodium Extended - Release Tablets, USP in the US(C)2013 M2 COMMUNICATIONS http://www.
Other agents that are approved for maintenance therapy include aripiprazole, lamotrigine, and olanzapine as monotherapy, and olanzapine, quetiapine, and ziprasidone as addon agents to lithium or divalproex.
Such key drugs as lamotrigine (GlaxoSmithKline's Lamictal and generics) face increased genetics competition, for example, as divalproex (Abbott/Sanofi-Aventis' Depakote and Depakote ER and generics).