dissociation constant

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Related to dissociation constant: equilibrium constant, dissociation constant of water, Acid dissociation constant

dis·so·ci·a·tion con·stant (Kd, K),

the equilibrium constant involved in the dissociation of a compound into two or more compounds or ions. The reciprocal of the association constant (2).


the act of separating or the state of being separated.

atrial dissociation
independent beating of the left and right atria, each with normal rhythm or with various combinations of normal rhythm, atrial flutter or atrial fibrillation.
atrioventricular dissociation
independent pacemakers in the atria and ventricles.
dissociation constant
the tendency of a solute to dissociate in solution.
hepatocyte dissociation
hepatocytes becomes detached from their neighboring cells, either generally or locally; a feature of death of the patient.
References in periodicals archive ?
The theoretical absorbances computed using the acidic dissociation constants, complex stability constants, salt solubility product, and molar absorptivities found for 4-nitroso-2,5-methylresorcinol and for its compounds formed with cobalt and iron(II) sulphates agree with the corresponding experimental results.
Acidic dissociation constants and absorptivities Characteristic AH Co Fe [A.
2+] complexes with apparent dissociation constants between 0.
Acid 1 (1063 molecules, 2893 pKas) Dissociation Constants of Organic Acids in Aqueous Solution, by G.
Base 2 (4275 molecules, 7844 pKas) Dissociation Constants of Organic Bases in Aqueous Solution, Supplement 1972, by D.
Conductometric, potentiometric, and spectrophotometric determination of dissociation constants of substituted benzoic acids in acetonitrile J.
The dissociation rates and equilibrium dissociation constants for each combinatorial mutant, determined by flow cytometry in the selection diluent, are listed in Table 2.
However, for understanding the inhibition mechanism as well as for rational design of the protein kinase bisubstrate inhibitors, it is necessary to evaluate the effectiveness of the interaction of these compounds with the enzyme not only on the IC50 level, but also on the level of the true dissociation constants.
Dan Sexton, investigator, Dyax Corporation, also spoke at the conference in a presentation entitled "A Microarray-Based Surface Plasmon Resonance Method for the Rapid Determination of Phage Display Derived Human Antibody Dissociation Constants.
The rate equation for the formation of product, the dissociation constants, and the enzyme mass balance are always given where applicable.
The apparent dissociation constants determined for hER-[alpha] and estrogen mimics obtained from sensor data via the competitive protocol are consistent with radioligand binding data (11-15).