disseminated gonococcal infection

disseminated gonococcal infection

STD A form of N gonorrhoeae infection affecting ±3% of Pts; it is 4-fold more common in ♀, especially during pregnancy and perimenstrual period Clinical Classic triad–dermatitis, tenosynovitis, migratory polyarthralgia; DGI follows mucosal infection–eg, genitourinary tract, rectum, oropharynx Clinical forms 1. Arthritis-dermatitis syndrome–tenosynovitis with skin rash and fever, often positive blood culture, asymmetric polyarthralgia;¹/₄ have monoarthralgia Sites Knee, elbow, wrist, metacarpophalangeal, ankle joints 2. Suppurative/septic arthritis–±¹/₃ of Pts, synovial fluid PMNs at 50,000–200,000 cells/mm3, maculopapular, pustular, vesicular or necrotic rash, often of torso, limbs, palms, soles; tenosynovitis in²/₃ of Pts typically of hands and fingers; rarely, DGI causes pericarditis, endocarditis, meningitis, death. See Neisseria gonorrhoeae.