diffuse cutaneous leishmaniasis

(redirected from disseminated cutaneous leishmaniasis)

dif·fuse cu·ta·ne·ous leish·man·i·a·sis

leishmaniasis caused by several New and Old World species and strains of Leishmania (L. mexicana amazonensis, L. m. pifanoi, possibly L. m. garnhami and L. m. venezuelensis; in Ethiopia, L. aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the nonulcerating, nonnecrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not seem to occur unless an acquired cellular hypersensitivity can develop.
See also: cutaneous leishmaniasis.

dif·fuse cu·ta·ne·ous leish·man·i·a·sis

(di-fyūs' kyū-tā'nē-ŭs lēsh'mă-nī'ă-sis)
A disorder caused by several New and Old World species and strains of Leishmania. The condition is associated with a suppressed cell-mediated immune response.
References in periodicals archive ?
Based on the clinical picture the hypotheses of disseminated cutaneous leishmaniasis, paracoccidioidomycosis, and malignant syphilis were raised.
Based on clinical and histological picture of chronic ulcerated dermatitis associated with leishmanias, the diagnosis of disseminated cutaneous leishmaniasis was established, the treatment with meglumine antimoniate 20mg/kg/day was started, and administered for 30 days.
On the basis of his clinical appearance the differential diagnoses in order of priority were disseminated cutaneous leishmaniasis deep fungal infection sarcoidosis and cutaneous lymphoma.
The differential diagnosis included lepromatous leprosy, secondary syphilis, disseminated cutaneous leishmaniasis, and cutaneous lymphoma.
If these lesions were due to leprosy, disseminated cutaneous leishmaniasis, or cutaneous lymphoma, penicillin therapy should not result in such rapid improvement.
He observed the parasite in smears from a person with disseminated cutaneous leishmaniasis, an uncommon manifestation of infection (25).
It includes an early lymphadenophathic form, the classic weeping cutaneous ulcers, disseminated cutaneous leishmaniasis, and mucosal disease (25,29,30).
amazonensis causes CL and 2 very serious manifestations of CL, disseminated cutaneous leishmaniasis (DCL) and ADCL (4).
Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis.

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