disease marker

disease marker

A substance or measurable parameter that can be used to identify the presence of a condition (e.g., markedly elevated PSA levels in an asymptomatic older male) or assess the status of known disease (e.g., haemoglobin A1c for a diabetic).
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The women underwent brachial artery ultrasound to assess brachial artery flow-mediated dilation (FMD), a preclinical disease marker that has been linked to clinical outcomes.
The biosensors are based on optical detection of a change in spectral response of the nanostructures upon binding a disease marker.
The use of a disease marker, levels of HIV RNA in patients' blood, played a key role in the development of the current highly effective therapies for AIDS that have made a vast difference in the survival and quality of life of HIV-infected individuals", said William E.
Koroshetz suggests that the long-sought Huntington's disease gene may encode a mitochondrial protein, but he cautions that no gene involved in energy production has yet been discovered near the Huntington's disease marker on chromosome 4.
We hope that with a better understanding of the steps leading to cancer development, we may be able to identify a precursor lesion or early disease marker such that we can diagnose cancer earlier, initiate appropriate treatment and improve patient survival.
But if you have a disease marker not affected by a dopaminergic therapy, then you would be able to test neuroprotective agents among smaller groups," he said.
Among other advances, Arnold and his colleagues posit that the ability to follow a signal in real time-to actually witness the detection of a single disease marker protein and track its movement-may yield new understanding of how proteins attach to antibodies.
Kinnula and colleagues point out that until now, no disease marker for COPD currently exists, despite extensive efforts by scientists to find one.
More specifically, a particular disease marker is bound with an antibody, which is then chemically colored or stained on the tissue.
The goal of the funded project is to refine the novel disease marker genome annotation system successfully prototyped by the company during Phase I of this grant.
These scanners are able to detect the smallest of tumors or plaque deposits rapidly, making them well-suited to the diagnosis of various cancer and heart disease markers.

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