epitope /ep·i·tope/ (ep´ĭ-tōp) an antigenic determinant (see under determinant ) of known structure.
epitope
epitope
ep·i·tope ( p  -t p )n. The surface portion of an antigen capable of eliciting an immune response and of combining with the antibody produced to counter that response. |
epitope
[ep′itōp]
Etymology: Gk epi + topos, place
epitope
see antigenic determinant.
continuous epitope
contiguous amino acid sequences in a linear array.
discontinuous epitope
one in which amino acids are in close proximity in the folded protein, but distant when unfolded.
epitope
Immunology Any site on a molecule–an antigenic determinant that can evoke antibody formation. See Idiotype, Immunogenicity.
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