discontinuation

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discontinuation

The act of concluding participation, before completing all protocol-required elements, in a trial by an enrolled subject. Subject discontinuation does not necessarily imply exclusion of the subject’s data from analysis.

Categories of discontinuation
• Dropout—Discontinuation of a trial by a subject or the discontinued subject him- or herself.
• Investigator initiated discontinuation (e.g., for cause).
• Loss to follow-up—Cessation of participation without notice or action by the subject.
• Sponsor initiated.
References in periodicals archive ?
For example, when the decision to discontinue a product is made by a manufacturer, lead time for ordering packaging materials should be 120 to 180 days, noted the white paper.
Simply put, although taxpayers must discontinue use of the mark-to-market method only with respect to nonfinancial customer paper, they should consider discontinuity use of the method for all securities.
Early use of a potent immune-system suppressor could stop the destruction of insulin-producing cells in diabetics, some of whom may then be able to discontinue insulin injections, according to reports this week on two recent clinical trials.
Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue ATRIPLA, Truvada, Emtriva or Viread and are co-infected with HIV and HBV.