disaccharidase


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disaccharidase

 [di-sak´ah-ri-dās″]
an enzyme that hydrolyzes disaccharides; in humans the disaccharidases are located in the brush border membrane of the small intestine and hydrolyze the oligosaccharides and disaccharides produced after luminal digestion of starches and other carbohydrates. See also disaccharide intolerance.

disaccharidase

/di·sac·cha·ri·dase/ (di-sak´ah-rĭ-dās″) an enzyme that catalyzes the hydrolysis of disaccharides.

disaccharidase

(dī-săk′ər-ĭ-dăs′, -dāz′)
n.
An enzyme, such as invertase or lactase, that catalyzes the hydrolysis of disaccharides to monosaccharides.

disaccharidase

[disak′äridās′]
in humans, the enzyme that hydrolyzes disaccharides. The disaccharidases are located in the brush border membrane of the small intestine and hydrolyze the oligosaccharides and disaccharides produced after luminal digestion of starches and other carbohydrates. See also disaccharide intolerance.

disaccharidase

any of a group of enzymes which are components of the brush border of the intestinal epithelium and which hydrolyze disaccharides to monosaccharides. They include lactase, maltase, sucrase and galactosidase. Enteric infections may cause a temporary deficiency of lactase leading to the development of an osmotic-type diarrhea. All disaccharidases are not present immediately following birth and feeding sucrose to young calves will result in diarrhea.
References in periodicals archive ?
A high level of disaccharidase may indicate an improvement of the digestive activity of small intestine (Claus et al.
Modulatory effect of fenugreek saponins on the activities of intestinal and hepatic disaccharidase and glycogen and liver function of diabetic rats.
The byproducts of bacterial fermentation, in addition to triggering gastrointestinal symptoms, further damage the small-intestinal mucosa and further decrease disaccharidase activity, which leads to a vicious cycle of more bacterial overgrowth and more pronounced intestinal damage.
Table 5A and B shows the acute effect of the Et0Ac and n-BuOH fractions on in vitro disaccharidase activity.
Longitudinal study of the human intestinal brush border membrane proteins: distribution of the main disaccharidases and peptidases.
These studies show a rather limited capacity of the intestinal mucosa to alter disaccharidase activities in response to changes in diet.
Previous report has indicted that administration with high dose (372 [micro]g/d) EGF in 21 days weaned piglets for three consecutive days, but not with low dose (124 [micro]g/d), can elevate jejunal disaccharidases (sucrase and lactase) activities (Jaeger et al.
However, Thomsen and Tasman-Jones (1982) observed decreased disaccharidase activities in the intestinal mucosa by dietary fibre.
Effect of diet upon intestinal disaccharidases and disaccharide absorption.
The mechanism of glucose reduction is likely to be multifactorial, and we suggest the factors related with the decreased activity of mucosal disaccharidases important for further investigation.