directly observed therapy

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directly observed therapy (DOT),

visual monitoring by a health care worker of patients' ingestion of medications, to ensure compliance in difficult or long-term regimens, such as in oral treatment for tuberculosis; a contentious aspect of some WHO programs.

directly observed therapy

Therapeutics A strategy for ensuring Pt compliance with therapy, where a health care worker or designee watches the Pt swallow each dose of prescribed drugs. See Patient compliance. Cf Directed observation.

directly observed therapy



Oral administration of a drug or of drugs to a patient under supervision to ensure the drug is swallowed. DOT is esp. important in treating patients with infectious diseases (e.g., HIV/AIDS or tuberculosis) in which development of drug-resistant microorganisms is likely to threaten public health if the drug is not taken exactly as prescribed.
References in periodicals archive ?
This trend was primarily due to changes in the demographic and risk factor composition of the cohort over time; after adjustment for demographic factors, directly observed therapy, drug use, and average HIV incidence in the patient's county of residence, this trend lost statistical significance (P= .
Treatment Failure: SIRTURO (TM) should be administered by directly observed therapy.
While Directly Observed Therapy Short Course (DOTS) with the existing anti-TB drugs, recommended by the WHO and the cornerstone of the Stop TB movement, will help to reduce TB in areas where it is rigorously practiced, new and more effective vaccines, diagnostics and drugs must be developed to truly achieve a significant level of control over the global TB epidemic.
By using a Video Directly Observed Therapy (VDOT) approach, this solution enables TB patients to record their daily treatments on smartphones, upload and store their videos securely on the cloud, and send the videos to health departments, where health officials can monitor treatment adherence remotely.
This woman is actually a TB patient who's been cured during an effective directly observed therapy course of treatment.