direct adverse effects

direct adverse effects, unfavorable outcomes as a direct result of treatment. Includes toxic effects and side effects of various duration.
References in periodicals archive ?
Importantly, however, the authors have inappropriately interpreted the lack of an effect of the MTHFR polymorphism on cardiovascular risk as a lack of direct adverse effects of homocysteine on the cardiovascular system.
direct adverse effects of the estrogen or progestin
On the other hand, the use of herbal preparations, intravenous hydrogen peroxide, colonies, and certain high-dose vitamins and minerals can produce direct adverse effects and need to be approached with more attention and caution.