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99m]Tc methylene diphosphonate is exquisitely sensitive because the radiotracer accumulates at sites of osteoblastic activity.
Atypical Femur Fractures Associated With Diphosphonate Use
16) Several studies have reported improved detection of both benign and malignant bone lesions with NaF PET compared to technetium methylene diphosphonate (TcMDP), although most of these were performed on adults.
Technetium-99m methylene diphosphonate (Tc-99m MDP) three-phase bone scintigraphy (TPBS) confirmed the clinical diagnosis of bilateral CRPS by detecting the mild or intense increased activity uptake in a dynamic, early blood pool, especially in delayed static images (Figure 3).
Tenebaum F, Schlumberga M, Bonnin F, et al: Usefulness of technetium-99m hydroxy methylene diphosphonate scans in localizing bone metastases of differentiated thyroid carcinoma.
99m]Technetium methylene diphosphonate bone scan may demonstrate the distribution and extent of gouty arthritis.
Losbona et al have suggested that 99mTc-methylene diphosphonate (99mTc-MDP) imaging is helpful in diagnosing early acute osteomyelitis.
Technetium-99m-labeled methylene diphosphonate ([Tc-99] MDP) bone scan is another test with high sensitivity (90%) but low specificity (78%) in the diagnosis of vertebral osteomyelitis.
Nuclear medicine detection of osteomyelitis is performed utilizing Technetium-99m methylene diphosphonate, either alone or in conjunction with Gallium-67 or Indium-111 labeled leukocytes.
6) There is little evidence to support the use of bone scintigraphy with Technetium-99 methylene diphosphonate ([sup.
A Tc-99m-methylene diphosphonate (MDP) bone scan revealed diffuse metastatic visceral calcifications on the lungs, myocardium and stomach (Figs 3a and b).
Duration of the effects of oral diphosphonate therapy in Paget's disease of bone.