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diphosphonate |
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diphosphonate /di·phos·pho·nate/ (di-fos´fŏ-nāt) 1. a salt, ester, or anion of a dimer of phosphonic acid, structurally similar to pyrophosphate but more stable. 2. any of a group of such compounds, having affinity for sites of osteoid mineralization and used as sodium salts to inhibit bone resorption as well as complexed with technetium Tc 99m for bone imaging. diphosphonate [difos′fonāt] any of a group of related phosphorus-containing compounds that are structurally similar to pyrophosphate but have enhanced stability to enzymatic and chemical hydrolysis and have affinity for sites of osteoid mineralization. They are used as sodium salts to inhibit bone resorption and are complexed with technetium Tc 99m for bone imaging. The group includes alendronate, etidronate, and pamidronate. Also called bisphosphonate. diphosphonate see bisphosphonates. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Technetium-99m-labeled methylene diphosphonate ([Tc-99] MDP) bone scan is another test with high sensitivity (90%) but low specificity (78%) in the diagnosis of vertebral osteomyelitis. a diphosphonate compound used for treatment of osteitis deformans, heterotopic ossification, and neoplasm-associated hypercalcemia, usually as the disodium salt. a diphosphonate compound used for treatment of osteitis deformans, heterotopic ossification, and neoplasm-associated hypercalcemia, usually as the disodium salt. |
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