was extracted and purified as reported previously.
, a naturally occurring furostanol saponin, suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinomacells.
Chen, "In vivo protective effects of diosgenin
against doxorubicin-induced cardiotoxicity," Nutrients, vol.
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin
Solasodine A3/4- sitosterol diosgenin
[6 7] triterpenes  steroidal saponins  and steroidal glycoalkaloids [10-12] are also reported from the fruit.
Variation in diosgenin
level in seed kernels among different provenances of Balanites aegyptiaca Del (Zygophyllaceae) and its correlation with oil content.
ameliorates cognition deficit and attenuates oxidative damage in senescent mice induced by D- galactose.
Other spice-derived phytochemicals, such as capsaicin, cardamonin, dibenzoylmethane, diosgenin
, gambogic acid, gingerol, thyoquinone, urosolic acid and zerumbone have been show the ability to suppress NF-kB activation in a similar manner.
in fenugreek is a steroidal sapogenin and is one of the compounds of fenugreek extract which acts as cortisone, and consequently, reduces anxiety (19).
Wild yam contains the glycoside diosgenin
, which has been shown to have an anaboliclike effect or the ability to increase muscle mass (18) Licorice root acts as an adaptogen and also has anti-inflammatory properties.
A phytoestrogen (plant estrogen) called diosgenin
found in wild yams can be converted in a laboratory into progesterone.
was used as a standard and the results obtained were expressed as mg diosgenin
equivalent per g of sample dry matter.