DMSO

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DMSO

 
dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has been used investigationally as an agent to increase the penetrability of other substances and as a topical analgesic and antiinflammatory. It has been approved by the U.S. Food and Drug Administration in a 50 per cent solution for direct instillation into the bladder for the treatment of interstitial cystitis. A 90 per cent solution, which has been approved only for veterinary use, is believed by some to be beneficial in the treatment of muscle sprains and strains, arthritis, spinal cord injuries, and the aftereffects of stroke when it is applied externally and absorbed by the skin. Claims that it is effective for treating these disorders in humans have not been validated by research studies. It has been shown to produce some short-term side effects.

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO

dimethyl sulfoxide.

DMSO

(dē′ĕm-ĕs-ō′)
n.
A colorless hygroscopic liquid, (CH3)2SO, obtained from lignin, used as an industrial solvent and in medicine as a penetrant to convey medications into the tissues.

DMSO

abbreviation for dimethyl sulfoxide.

DMSO

Alternative medicine
A substance that occurs naturally in minute amounts in certain foods, which has industrial and health-related applications. Animal studies have shown it to have analgesic, anti-inflammatory, antimicrobial, vasodilatory and other properties; up to the 1960s, DMSO had been administered orally, topically or parenterally by mainstream physicians for various conditions, including arthritis, bursitis, cancer, emphysema, mental illness and pain. In the face of its association with lenticular degeneration, DMSO was removed from general use; some practitioners of alternative healthcare continue to recommend DMSO for these and other uses.
 
Toxicity
Topical DMSO is associated burning, itching and an unpleasant odour.
 
Mainstream medicine
DMSO is FDA-approved for treating interstitial cystitis, and may be of use in treating scleroderma, sprains, arthritis, cerebrovascular accidents, familial amyloidotic polyneuropathy and acetaminophen hepatotoxicity. DMSO reduces the ice crystals formed in frozen section tissues from the operating suite, and may be an effective cryopreservative.

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO,

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO

dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has bacteriostatic, anti-inflammatory, analgesic, radioprotective, fibrinolytic and vasodilative properties, and inhibits cholinesterase and granulation tissue. DMSO also has been used as an agent to increase the penetrability of other substances. Only approved for veterinary use, it has found varied applications as a topical treatment for musculoskeletal conditions in horses and skin diseases, mainly in dogs.
References in periodicals archive ?
In order to ensure that dimethylsulphoxide and ethanol per se did not interfere with the antimicrobial activity of the products under assay, a control test was also carried out on inoculated broth supplemented with only dimethylsulphoxide and ethanol at the same concentration used in the assays.
Since the conductivity of solvent combinations such as ethylene carbonate (EC), propylene carbonate (PC), dimethylacetamide (DMA), dimethylformamide (DMF), and dimethylsulphoxide (DMSO) are about [10.
1 and were impregnated with 16 micro liters of the plant extract dissolved in dimethylsulphoxide (DMSO) (100 microgram extract/ml.
Dimethylsulphoxide (DMSO), methanol and other reagents of analytical grade were obtained from Merck (Darmstadt, Germany).
The hardening effect of dimethylsulphoxide on the mouse zona pellucida requires the presence of an oocyte and is associated with a reduction in the number of cortical granules present.
The dried plant extracts were dissolved in 5 per cent dimethylsulphoxide (DMSO; Merck, Germany) and then in sterile water, to reach a final concentration of 20 mg/ml and sterilized by filtration by 0.
Aqueous extract, EtOH extract, verticine, ebeiedine and suchengbeisine were dissolved in dimethylsulphoxide and treated in culture medium (final concentrations of dimethylsulphoxide were 0.
The dialdehyde (NBOB) and Schiff base polymer (PNBOBen) were soluble in various common organic solvents including tetrahydrofuran (THF), dimethylformamide (DMF), dimethylacetamide (DMAc) and dimethylsulphoxide (DMSO).
Dimethylsulphoxide (M&B, England), hydrogen peroxide (Merck, Germany) and 2, 2--diphenyl-1-picrylhydrazyl (DPPH), ascorbic acid, Butylated hydroxylanisole (BHA) and a-tocopherol were obtained from Sigma Chemical Co (St Louis, MO).
One [micro]l SYBR-14 of 1 mM solution in dimethylsulphoxide (DMSO) was diluted with 49 [micro]l HEPES-buffered saline solution (10 mM HEPES, 150 mM NaCl, pH 7.
Kolaviron (100 mg/kg body weight), dissolved in dimethylsulphoxide (DMSO) was administered by gastric gavage five times weekly.
The monomer MBPC exhibits good solubility in polar aprotic solvents, dimethylformamide (DMF) and dimethylsulphoxide (DMSO).