dilated cardiomyopathy

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Related to dilated cardiomyopathy: hypertrophic cardiomyopathy

di·lat·ed car·di·o·my·op·a·thy

decreased function of the left ventricle associated with its dilation; most patients have global hypokinesia, although discrete regional wall movement abnormalities may occur; usually manifested by signs of overall cardiac failure, with congestive findings, as well as by fatigue indicative of a low output state.

dilated cardiomyopathy

Cardiology The most common cardiomyopathy in the US, which is usually idiopathic and characterized by ↑ ventricular size and impaired ventricular function Etiology Infection–eg coxsackievirus, CMV, HIV, diphtheria, trichinosis, inflammation–eg connective tissue disease, sarcoidosis, metabolic–eg hypothyroidism, thyrotoxicosis, DM, Cushing's disease, thiamine, selenium deficiency, or toxic–eg cocaine, antiretroviral agents, lead, cobalt, ethanol, phenothiazines insults; ±20% of DCs, there is a familial component Prognosis Often progresses to CHF accompanied by mitral and tricuspid valve insufficiency Complications Conduction defects–eg atrial & ventricular tachyarrhythmias and fibrillation Management Supportive–eg rest, weight control, smoking cessation, ↓ physical activity during exacerbation; therapies that may be effective include ACE inhibitors, anticoagulation, digoxin, diuretics, implantable defibillators, nitrates, potassium, magnesium repletion Investigational modalities Amiodarone, amlodipine, beta-blockers, dual-chamber pacing, felodipine, pimobendan, vesnarinone; recombinant hGH has been reported to ↑ myocardial mass and ↓ left ventricular chamber size, resulting in improved hemodynamics, myocardial energy metabolism, clinical status

Beck·er dis·ease

(bek'ĕr di-zēz')
An obscure South African cardiomyopathy leading to rapidly fatal congestive heart failure and idiopathic mural endomyocardial disease.
Synonym(s): dilated cardiomyopathy.

Dilated cardiomyopathy

Also called congestive cardiomyopathy; cardiomyopathy in which the walls of the heart chambers stretch, enlarging the heart ventricles so they can hold a greater volume of blood than normal.


a state of dilatation.

dilated cardiomyopathy
see congestive cardiomyopathy.
dilated pupil syndrome
see feline dysautonomia (Key-Gaskell syndrome).
References in periodicals archive ?
In the present series of 31 cases of dilated cardiomyopathy males were affected more than the female population similar to other studies.
Differential interventricular expression of microRNAs-21, -93, -151, -221 and -582, in dilated cardiomyopathy with biventricular dysfunction.
Other important cause of dilated cardiomyopathy like presentation in young child is anomalous origin left coronary artery from pulmonary artery.
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice.
Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy.
Induction of cardiomyopathy in severe combined immunodeficiency mice by transfer of lymphocytes from patients with idiopathic dilated cardiomyopathy.
Dilated Cardiomyopathy (DCM) occurs predominantly in males as compared to females (Borgarelli et al.
The trial enrolled 14 patients with either ischemic or non-ischemic dilated cardiomyopathy with left ventricular ejection fraction (LVEF) of 35 percent or below and New York Heart Association (NYHA) Class III or Ambulatory Class IV heart failure.
DISCUSSION: Dilated cardiomyopathy is a syndrome characterized by cardiac enlargement and impaired systolic function of one or both the ventricles.
Dilated cardiomyopathy (DCM) is a cardiac muscle disease, characterized by dilatation and impaired contraction of the left ventricle or both ventricles, and leads to progressive heart failure and sudden or heart failure-related death [1].
It also reviews key players involved in the therapeutic development for Dilated Cardiomyopathy and special features on late-stage and discontinued projects.
Peripartum cardiomyopathy is one of the rare causes of dilated cardiomyopathy in parturients with a great diagnostic difficulty.