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dihydrostreptomycin

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dihydrostreptomycin
an aminoglycoside antibiotic produced by the hydrogenation of streptomycin; ototoxic with damage to sensory end organs.
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Major groups of traditional ototoxic agents in humans Aminoglycosides Cytotoxic agents Amikacin Bleomycin Dihydrostreptomycin Carboplatinum Gentamicin Cisplatinum Kanamycin Nitrogen mustard Neomycin Vincristine Netilmicin Streptomycin Others Tobramycin Acetylsalicylic acid Arsenicals Loop diuretics Quinine Table 2.
Safety and efficacy of topical quinolones by Ear, Nose and Throat Journal
Unlike its predecessor, dihydrostreptomycin is much more cochleotoxic than it is vestibulotoxic; in fact, it is almost exactly as cochleotoxic as streptomycin is vestibulotoxic.
Characteristics of systemic and topical agents implicated in toxicity ... by Roland, Peter S. / Ear, Nose and Throat Journal
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