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dihydropyrimidine dehydrogenase (NADP) |
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dihydropyrimidine dehydrogenase (NADP) /di·hy·dro·py·rim·i·dine de·hy·dro·gen·ase (NADP)/ (-pi-rim´i-den de-hi´dro-jen-as) an enzyme catalyzing a step in the catabolism of pyrimidines; deficiency results in elevated plasma, urine, and cerebrospinal levels of pyrimidines, cerebral dysfunction in children, and hypersensitivity to 5-fluorouracil in adults. |
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