dihydropteridine reductase

(redirected from dihydrobiopterin reductase)

di·hy·dro·pter·i·dine re·duc·tase

(dī-hī-drō-ter'i-dēn rē-dŭk'tās),
An enzyme that catalyzes the reversible formation of tetrahydrobiopterin from dihydrobiopterine using NADPH; a deficiency of this enzyme can result in malignant hyperphenylalaninemia.
References in periodicals archive ?
In the presence of 5-MTHF, the enzyme dihydrobiopterin reductase can reduce quininoid dihydrobiopterin to tetrahydrobiopterin (BH4) (12).