digitoxin

digitoxin /dig·i·tox·in/ (-tok´sin) a cardiotonic glycoside from Digitalis purpurea and other Digitalis species; used similarly to digitalis.

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dig·i·tox·in (dj-tksn)

n.

A secondary cardioactive glycoside that is derived from and similar in effect to digitalis but that is more completely absorbed from the gastrointestinal tract.

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digitoxin

[dij′itok′sin]

a cardiac glycoside obtained from leaves of Digitalis purpurea. Digitoxin differs in many ways from digoxin, including having a far greater half-life and a different route of elimination.

indications It is prescribed in the treatment of congestive heart failure and certain cardiac arrhythmias.

contraindications Ventricular fibrillation, ventricular tachycardia, or known hypersensitivity to this drug prohibits its use.

adverse effects The most serious adverse reactions are cardiac arrhythmias and heart block, disorientation, and visual disturbances.

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digitoxin

(dij´itok´sin),
n brand names: Crystodigin, Digitaline;
drug class: cardia glycoside;
action: inhibits the formation of sodium-potassium ATPase, which makes more calcium available for contractile proteins;
uses: congestive heart failure (CHF), atrial fibrillation, paroxysmal atrial flutter, atrial tachycardia.

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digitoxin

a cardiotonic glycoside obtained from Digitalis purpurea and other species of the same genus; used in the treatment of congestive heart failure.

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digitoxin

Cardiology A cardiac glycoside used like digoxin, which binds more strongly to proteins, but for a similar pharmacologic effect, requires a 10-fold greater concentration