digitalis toxicity

digitalis toxicity

Digoxin toxicity Cardiology Clinical findings of digoxin overdose Clinical Loss of appetite, N&V, defects in color vision–reds and greens, or seeing halos around lights, psychotic changes, weakness, fatigue, or dizziness; new onset of arrhythmias typical of DT include frequent or multiform PVCs, ventricular tachycardia, atrial tachycardia with block, accelerated junctional rhythms, Wenckebach rhythms, and A Fib with slowed ventricular responses, hyperkalemia Management Discontinue digoxin, monitor arrhythmias with telemetry, correct acid-base, electrolyte, and volume abnormalities; treat medical conditions–eg, hypoxia, ischemia, and arrhythmias; arrhythmias are common and often respond to lidocaine and/or dilantin; in extreme emergencies, digoxin antibody fragments, which bind the active portion of the digoxin molecule, may be needed to ↓ DT.
References in periodicals archive ?
Other conditions, such as inferior myocardial infarction or digitalis toxicity, also may produce block-acceleration atrioventricular dissociation (1).
Cholestyramine has been used as a treatment for intrahepatic cholestasis of pregnancy and as an antidote for some types of diarrhea, cholordecone pesticide poisoning, and digitalis toxicity.
In fact, antibody therapy is now available for a variety of situations in which natural antibody immunity is not likely to be effective, including prevention of re-stenosis after coronary angioplasty and the therapy for venomous animal bites, digitalis toxicity, breast cancer, and Crohn disease (reviewed in [77]).
MED3 DIGITALIS TOXICITY, HYPERKALEMIA, AND ACUTE RENAL FAILURE.
He and co-workers have already begun a multicenter study involving 300 people with congestive heart failure, in search of a link between potentially fatal digitalis toxicity and circulating levels of the ouabain-like cardiac glycoside.
The early investigators also suggested that magnesium in hard water might be useful in maintaining a normal heart rhythm in the presence of ischemia or digitalis toxicity, or in acute alcohol- or diuretic-induced hypomagnesemia (low blood magnesium).
Digitalis toxicity can cause vomiting, nausea, dizziness, low blood pressure, cardiac instability and bradycardia - several reports of illness and injuries have already been reported.
Digitalis toxicity is the major complication, pending a full history of digitalis dosage, blood tests for renal failure, and measurement of serum digoxin and potassium.
David Zeltser and his associates at Tel Aviv University reviewed the records of all 169 consecutive patients at their institution who were admitted during 1999-2003 with second- or third-degree AV block that was not related to acute MI, vasovagal syncope, digitalis toxicity, or radiofrequency ablation.
Pharmacokinetic aspect of digoxin-specific Fab therapy in the management of digitalis toxicity.