diflunisal


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diflunisal

 [di-floo´nĭ-sal]
a salicylic acid derivative that, like aspirin, has analgesic and antiinflammatory properties, although no antipyretic effects, but has fewer side effects than aspirin, does not affect bleeding time or function, and has a long half-life that permits twice daily dosage. It is used in the treatment of rheumatic and nonrheumatic inflammatory disorders, gout and calcium pyrophosphate deposition disease, dysmenorrhea, and vascular headaches.

diflunisal

/di·flu·ni·sal/ (di-floo´nĭ-sal) a nonsteroidal antiinflammatory drug that lacks antipyretic activity; used in the treatment of rheumatic and nonrheumatic inflammatory disorders, gout and calcium pyrophosphate deposition disease, dysmenorrhea, and vascular headaches.

diflunisal

(dī-flo͞o′nĭ-săl′, -sôl′)
n.
A nonsteroidal anti-inflammatory drug that is a derivative of salicylic acid and is used to treat inflammation and mild to moderate pain.

diflunisal

[dīflo̅o̅′nisal]
a nonsteroidal antiinflammatory drug.
indications It is prescribed for the treatment of mild to moderate pain and inflammation in osteoarthritis and other musculoskeletal disorders.
contraindications Hypersensitivity to aspirin and other nonsteroidal antiinflammatory drugs or known sensitivity to this drug prohibits its use.
adverse effects The most serious adverse reactions are GI pain, diarrhea, peptic ulcer, anorexia, anaphylactoid reactions with bronchospasm, and edema.

diflunisal

A non-steroidal pain-killing and anti-inflammatory drug (NSAID). It is a derivative of SALICYLIC ACID and is used to control symptoms in OSTEOARTHRITIS and other painful conditions. A brand name is Dolobid.

diflunisal

(dīfloo´nəsal´),
n brand name: Dolobid;
drug class: salicylate derivative, nonsteroidal antiinflammatory;
action: inhibits prostaglandin synthesis;
uses: mild to moderate pain, symptoms of rheumatoid arthritis and osteoarthritis.

diflunisal

a salicylic acid derivative that, like aspirin, has analgesic and anti-inflammatory properties.
References in periodicals archive ?
Dolobid is the Merck registered trademark for diflunisal.
CRx-401 contains a low dose of diflunisal and bezafibrate, neither of which is indicated for the treatment of diabetes on its own, but which have been shown in preclinical studies to act synergistically to increase insulin sensitivity and lower plasma glucose.
It currently has lawsuits pending against the makers of Children's Advil, and the NSAID diflunisal (Dolobid), as well as the antibiotics Zithromax and Amoxicillin, a synthetic penicillin.
For the detection of ALP activity, 100 [micro]L of 1 mmol/L diflunisal phosphate diluted in substrate buffer (1 mmol/L Mg[Cl.
Moldin stated that the decline in first quarter sales from the immediately preceding quarter resulted from a combination of factors, including expected fall-off from the prior quarter which saw the launch of new diclofenac sodium, diflunisal and indapamide products and the commencement of contract manufacture of the modified release morphine product Kadian(TM), and changes in buying practices by certain of the company's customers.
Modulation of reversible and covalent interaction of diflunisal acyl glucuronide and its isomers with human plasma in vitro.
received approval to market diclofenac delayed-release tablets, diflunisal tablets and indapamide tablets earlier this year.
Diflunisal phosphate [100 [micro]L of a 1 mmol/L solution in substrate buffer (0.
The recent approvals of diclofenac, diflunisal, and indapamide have the potential to help improve its earnings while it digests the new acquisitions and completes its management reorganization.
This new drug is the third FDA approval received by the company so far this calendar year, with diclofenac delay-release tablets and diflunisal tablets having been approved respectively in March and May," Moldin said.
The alkaline phosphatase activity was measured by adding the substrate diflunisal phosphate, incubating for 10 min, and then adding a [Tb.
has received approval from the Food and Drug Administration to market diflunisal tablets, it was announced today by Richard F.