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diffuse scleroderma

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diffuse scleroderma.


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An association between occupational exposures of inhaled particulates and autoimmunity was postulated as early as 1914, when Bramwell (1914) reported increased frequency of diffuse scleroderma (SSc) in stone masons.
One notable exception is patients with diffuse scleroderma disease of less than 4 years' duration.
Early in 1999, Connetics initiated a pivotal study with relaxin in diffuse scleroderma, the most severe form of the disease.
 
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