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diffuse cutaneous leishmaniasis

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diffuse cutaneous leishmaniasis
n.
A chronic form of leishmaniasis caused by Leishmania aethiopia in Ethiopia and Kenya and by various subspecies of L. mexicana in Central and South America, and characterized by nonulcerating, non-necrotizing skin lesions that spread over the body. Also called anergic leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa.


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Diffuse cutaneous leishmaniasis develops in the setting of infections with L.
After promising results were obtained with miltefosine in a patient with anergic diffuse cutaneous leishmaniasis (ADCL) in Venezuela (2), the patient received 150 mg/day oral miltefosine (Impavido, Zentaris, Germany) for 98 days and the lesional parasite load was quantified with quantitative nucleic acid sequence-based amplification (3).
 
 
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