diffuse alveolar damage
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a·dult res·pi·ra·to·ry dis·tress syn·drome (ARDS),
acute lung injury from a variety of causes, characterized by interstitial or alveolar edema and hemorrhage as well as perivascular pulmonary edema associated with hyaline membrane formation, proliferation of collagen fibers, and swollen epithelium with increased pinocytosis.
diffuse alveolar damageA term of art referring to the histologic findings in adult respiratory distress syndrome (ARDS), which is characterised by an acute onset of diffuse pulmonary infiltrates.
AIDS, air embolism, fat embolism, aspiration of gastric content, cardiopulmonary bypass, connective tissue disease (lupus, rheumatoid arthritis, scleroderma, dermatomyositis), DIC, drugs (either therapeutic—e.g., bleomycin, busulfan, cytoxan, methotrexate, nitrofurantoin—or drugs of abuse), heat injury, haemosiderosis, high altitude, iatrogenic (PEEP), infection (viruses, e.g., herpes, CMV; protozoans, e.g., Toxoplasma gondii, Pneumocystis jiroveci), molar pregnancy, noxious fumes (e.g., beryllium, cadmium, mercury, zinc), toxins (e.g., ammonia, kerosene, paraquat, phosgene), gases (e.g., CO2, NO2), (acute) pancreatitis, radiation, sepsis and endotoxins, shock, uraemia.
Goodpasture’s syndrome, hypersensitivity pneumonitis, multisystem organ failure, pneumonia (aspiration, bacterial, eosinophilic, nosocomial, Pneumocystis jiroveci, ventilator-related), respiratory failure, sepsis, shock (haemorrhagic, septic, toxic), perioperative lung management, toxicity (heroin, paraquat, salicylates), transfusion reaction, tumor lysis, ventilation.